ZYME
Zymeworks Inc. · Healthcare · Biotechnology
Last
$23.33
−$0.48 (−2.02%) 4:00 PM ET
After hours $23.29 −$0.04 (−0.17%) 6:37 AM ET
Prev close $23.81
Open $23.65
Day high $23.65
Day low $22.92
Volume 489,373
Avg vol 613,567
Mkt cap
$1.76B
P/E ratio
-27.45
FY Revenue
$134.48M
EPS
-0.85
Gross Margin
100.00%
Sector
Healthcare
AI report sections
ZYME
Zymeworks Inc.
No AI report section text found yet for this symbol.
Volume vs average
Intraday (cumulative)
+12% (Above avg)
Vol/Avg: 1.12×
RSI
53.76 (Neutral)
Neutral (40–60)
MACD momentum
Intraday
+0.01 (Strong)
MACD: 0.03 Signal: 0.03
Short-Term
+0.22 (Strong)
MACD: -0.07 Signal: -0.29
Long-Term
+0.18 (Strong)
MACD: -0.61 Signal: -0.79
Intraday trend score 53.00

Latest news

ZYME 12 articles Positive: 8 Neutral: 3 Negative: 1
Neutral GlobeNewswire Inc. • Na
Zymeworks To Report Fourth Quarter and Full Year 2025 Financial Results and Host Conference Call on March 2, 2026

Zymeworks Inc. announced it will report its fourth quarter and full year 2025 financial results on March 2, 2026, followed by a conference call at 8:30 am ET. The biotechnology company is managing a portfolio of licensed healthcare assets and developing multifunctional biotherapeutics, with key products including Ziihera and partnerships with BeOne Medicines and Jazz Pharmaceuticals for commercialization rights.

ZYME ONC JAZZ financial results fourth quarter 2025 biotherapeutics Ziihera zanidatamab
Sentiment note

The article is primarily an announcement of financial results reporting and conference call scheduling. While the company describes its portfolio and partnerships positively, there is no new clinical data, regulatory approval, or business development news that would warrant a positive or negative sentiment. The tone is factual and informational.

Neutral GlobeNewswire Inc. • Na
Zymeworks Announces Participation in Upcoming Investor Conferences

Zymeworks Inc. announced that its management will participate in multiple investor conferences in February and March 2026, including Citi's Virtual Oncology Leadership Summit, TD Cowen Health Care Conference, Leerink Global Healthcare Conference, and Citizens Life Science Conference. The company continues to advance its portfolio of licensed healthcare assets and biotherapeutics pipeline.

ZYME ONC JAZZ investor conferences biotherapeutics Ziihera zanidatamab HER2-targeted
Sentiment note

The announcement is primarily informational regarding conference participation. While the company mentions positive Phase 3 results for Ziihera and strategic priorities, the main article focuses on logistical conference details rather than substantive business developments or financial performance updates.

Positive Benzinga • Vandana Singh
Jazz Pharmaceuticals' Drug Extends Survival Past Two Years in Advanced Stomach Cancer Trial

Jazz Pharmaceuticals announced positive Phase 3 trial results for Ziihera (zanidatamab-hrii) in treating HER2-positive gastroesophageal adenocarcinoma. The triplet therapy combining Ziihera with tislelizumab and chemotherapy achieved a median overall survival of 26.4 months, the longest reported in a Phase 3 GEA trial, representing a 28% reduction in death risk. The doublet therapy also showed strong results with median OS of 24.4 months. Jazz shares rose 2.07% following the announcement.

JAZZ ZYME Phase 3 trial gastroesophageal adenocarcinoma Ziihera overall survival HER2-positive cancer clinical trial results
Sentiment note

Partner in the successful Phase 3 trial for Ziihera development. Positive trial results enhance the commercial potential of the drug candidate.

Positive GlobeNewswire Inc. • Zymeworks Inc.
Ziihera® (zanidatamab-hrii) Combinations Achieve Unprecedented Results in First-Line HER2+ Locally Advanced or Metastatic GEA including more than Two Years Median Overall Survival Benefit

Zymeworks announced positive Phase 3 HERIZON-GEA-01 results for Ziihera (zanidatamab-hrii) in combination with chemotherapy, with or without tislelizumab, for first-line treatment of HER2-positive gastroesophageal adenocarcinoma. The trial demonstrated statistically significant improvements in progression-free survival (approximately 35% risk reduction) and overall survival (26.4 months median, representing a 7+ month improvement over trastuzumab). Zymeworks is eligible to receive up to $440 million in milestone payments from regulatory approvals across major markets.

ZYME JAZZ ONC HER2-positive gastroesophageal cancer zanidatamab Phase 3 trial overall survival benefit first-line treatment
Sentiment note

Positive Phase 3 trial results demonstrating significant clinical benefits (7+ month OS improvement, longest reported in GEA Phase 3 trials), potential to become new standard of care, and substantial near-term milestone payments ($440M) from partners Jazz and BeOne across major markets (US, Europe, Japan, China). Results validate the company's Azymetric platform technology.

Positive GlobeNewswire Inc. • Zymeworks Inc.
Zymeworks Announces Participation in Upcoming Investor Conferences

Zymeworks Inc. will participate in two upcoming healthcare investor conferences in Miami, including one-on-one meetings and fireside chats, highlighting their biotechnology portfolio and licensed healthcare assets.

ZYME ONC JAZZ biotechnology healthcare investor conferences biotherapeutics licensed assets
Sentiment note

Company is actively engaging with investors, showcasing its diverse pipeline of novel biotherapeutics and strategic partnerships with global biopharmaceutical companies

Positive Benzinga • Vandana Singh
Zymeworks, Jazz Pharmaceuticals Stocks Climb On Robust Gastroesophageal Trial Outcomes And Upcoming Regulatory Plans

Zymeworks, Jazz Pharmaceuticals, and BeOne Medicines reported positive Phase 3 trial results for Ziihera in treating HER2-positive gastroesophageal adenocarcinoma, demonstrating significant improvements in progression-free and overall survival.

ZYME JAZZ ONC gastroesophageal cancer clinical trial HER2-positive pharmaceutical
Sentiment note

Stock surged 36.20% due to successful clinical trial results and potential future milestone and royalty payments

Positive GlobeNewswire Inc. • Zymeworks Inc.
Zymeworks Announces Participation in Upcoming Investor Conferences

Zymeworks, a clinical-stage biotechnology company, announced participation in upcoming investor conferences and highlighted its progress in developing biotherapeutics for cancer and other diseases, including the FDA-approved zanidatamab for biliary tract cancer.

ZYME ONC JAZZ biotechnology biotherapeutics cancer zanidatamab clinical trials
Sentiment note

Company has FDA-approved drug, ongoing clinical trials, strategic partnerships, and is presenting at investor conferences, indicating growth and potential

Neutral GlobeNewswire Inc. • Zymeworks Inc.
Zymeworks to Report Third Quarter 2025 Financial Results and Host Conference Call on November 6, 2025

Zymeworks will report its Q3 2025 financial results on November 6, 2025, and host a conference call to discuss financial performance and provide a corporate update.

ZYME ONC JAZZ biotechnology financial results conference call biotherapeutics cancer treatment
Sentiment note

Standard financial reporting announcement with no significant positive or negative indicators

Positive GlobeNewswire Inc. • Zymeworks Inc.
Zymeworks Appoints Dr. Adam Schayowitz as Acting Chief Development Officer

Zymeworks has appointed Dr. Adam Schayowitz as Acting Chief Development Officer, leveraging his extensive oncology drug development experience to advance the company's therapeutic pipeline and strategic partnerships.

ZYME PFE biotechnology oncology drug development biotherapeutics partnerships
Sentiment note

The company is expanding its leadership team with an experienced executive, advancing its clinical pipeline, and strengthening strategic partnerships

Negative GlobeNewswire Inc. • Zymeworks Inc.
Zymeworks Announces Decision to Discontinue Clinical Development of ZW171, a Mesothelin-directed T cell Engager

Zymeworks has decided to voluntarily discontinue clinical development of ZW171, a T cell engager targeting gynecological, thoracic, and digestive system cancers, after dose escalation phase revealed dose-limiting toxicities.

ZYME ZW171 T cell engager clinical development cancer mesothelin
Sentiment note

Company voluntarily discontinued clinical development of ZW171 due to unfavorable toxicity profile and unlikely benefit-risk balance, indicating a setback in their drug development pipeline

Positive GlobeNewswire Inc. • Zymeworks Inc.
Zymeworks Announces Participation in Upcoming Investor Conferences

Zymeworks, a clinical-stage biotechnology company, will participate in multiple investor conferences in September 2025, including events hosted by Citi, Wells Fargo, Cantor, and Morgan Stanley, to discuss its biotherapeutics pipeline and recent developments.

ZYME ONC JAZZ biotechnology biotherapeutics investor conferences cancer treatment zanidatamab
Sentiment note

Company is showcasing its pipeline, has received regulatory approvals for zanidatamab, and is actively advancing clinical trials for multiple product candidates

Positive GlobeNewswire Inc. • Zymeworks Inc.
Zymeworks to Report Second Quarter 2025 Financial Results and Host Conference Call on August 7, 2025

Zymeworks, a clinical-stage biotechnology company, will report its Q2 2025 financial results on August 7, 2025, and participate in upcoming investor conferences. The company has received regulatory approvals for zanidatamab, a HER2-targeted bispecific antibody for biliary tract cancer treatment.

ZYME ONC JAZZ biotechnology zanidatamab HER2 biliary tract cancer clinical trials
Sentiment note

Company has received regulatory approvals in multiple territories, advancing its pipeline, and participating in investor conferences, indicating growth and positive momentum

News and sentiment labels describe article tone and are provided for research purposes only. They are not trading recommendations or forecasts.
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