PCVX
Vaxcyte, Inc. · Healthcare · Biotechnology
Last
$61.70
+$1.70 (+2.83%) 4:00 PM ET
After hours $62.67 +$0.98 (+1.58%) 4:05 PM ET
Prev close $60.00
Open $60.02
Day high $61.86
Day low $59.11
Volume 1,308,562
Avg vol 1,541,886
Mkt cap
$8.86B
P/E ratio
-10.98
EPS
-5.62
Sector
Healthcare
AI report sections
PCVX
Vaxcyte, Inc.
PCVX trades near its short-term moving averages with positive 1–6 month price momentum but still reflects a deep 12‑month drawdown and high historical volatility within a wide 52‑week range. The technical backdrop shows multiple bullish momentum and breakout signals, while fundamentals remain characterized by large losses, negative free cash flow, and deteriorating earnings despite a cash-rich, low‑debt balance sheet. Valuation metrics highlight loss‑making operations and negative free cash flow yield alongside ample liquidity and no balance‑sheet leverage, with short interest and news flow indicating a mixed but engaged market stance.
AI summarized at 6:31 PM ET, 2026-01-21
AI summary scores
INTRADAY: 68 SWING: 72 LONG: 38
Volume vs average
Intraday (cumulative)
+36% (Above avg)
Vol/Avg: 1.36×
RSI
62.49 (Strong)
Strong (60–70)
MACD momentum
Intraday
+0.02 (Strong)
MACD: 0.11 Signal: 0.09
Short-Term
+0.39 (Strong)
MACD: 2.70 Signal: 2.30
Long-Term
+0.48 (Strong)
MACD: 3.92 Signal: 3.44
Intraday trend score 67.82

Latest news

PCVX 12 articles Positive: 10 Neutral: 1 Negative: 1
Positive Benzinga • Globe Newswire
Vaxcyte Announces Closing of $632.5 Million Public Offering Including Full Exercise of Underwriters' Option to Purchase Additional Shares

Vaxcyte, Inc. (NASDAQ: PCVX) announced the successful closing of its underwritten public offering, raising $632.5 million gross proceeds through the sale of 12,650,000 shares of common stock at $50 per share, including the full exercise of underwriters' option for 1,650,000 additional shares. The funds will support the company's clinical-stage vaccine development programs.

PCVX public offering vaccine development pneumococcal conjugate vaccine clinical trials capital raise VAX-31 VAX-24
Sentiment note

The company successfully completed a substantial $632.5 million capital raise with full exercise of underwriters' options, indicating strong investor confidence. The funding supports advancement of multiple vaccine candidates in clinical development, including Phase 3 programs for VAX-31, which represents a significant therapeutic advancement in pneumococcal disease prevention.

Positive GlobeNewswire Inc. • Na
Vaxcyte Announces Pricing of $550 Million Public Offering

Vaxcyte, Inc. (Nasdaq: PCVX), a clinical-stage vaccine company, announced the pricing of an underwritten public offering of 11 million shares at $50 per share, generating $550 million in gross proceeds. The offering is expected to close on February 2, 2026. The company is developing VAX-31, a 31-valent pneumococcal conjugate vaccine candidate in Phase 3 adult and Phase 2 infant clinical programs, along with other vaccine candidates in its pipeline.

PCVX public offering pneumococcal vaccine VAX-31 clinical-stage vaccine development capital raise
Sentiment note

The company successfully priced a substantial $550 million public offering, demonstrating investor confidence and providing significant capital to advance its clinical vaccine programs, particularly VAX-31 which is in advanced-stage development (Phase 3 adult and Phase 2 infant trials).

Positive GlobeNewswire Inc. • Vaxcyte, Inc.
Vaxcyte Advances Adult and Infant Programs for VAX-31, a Potential Best-in-Class, Next-Generation Pneumococcal Conjugate Vaccine

Vaxcyte announced progress on VAX-31, its 31-valent pneumococcal conjugate vaccine, with first participants dosed in the OPUS-2 Phase 3 adult trial evaluating concomitant administration with seasonal influenza vaccine. The company plans to initiate OPUS-3 Phase 3 trial in Q1 2026 for previously vaccinated adults and expects topline data from OPUS-1 in Q4 2026 and OPUS-2/OPUS-3 in H1 2027. For the infant indication, enrollment of 905 participants in the Phase 2 dose-finding study is complete, with data expected by end of H1 2027. Vaxcyte is also establishing manufacturing presence in North Carolina with a planned $1 billion commitment.

PCVX VAX-31 pneumococcal conjugate vaccine Phase 3 clinical trial OPUS-2 OPUS-3 adult indication infant indication
Sentiment note

Company is advancing multiple Phase 3 clinical programs for VAX-31 with FDA alignment, completed enrollment in infant Phase 2 study, received expanded Breakthrough Therapy designation, and is investing significantly in U.S. manufacturing infrastructure. Multiple near-term data readouts expected support regulatory pathway toward BLA submission.

Positive Benzinga • Vandana Singh
Thermo Fisher Launches Four-Part Bond Offering Ahead Of Possible Government Shutdown

Thermo Fisher Scientific is issuing a four-part bond offering in the U.S. investment-grade market, with proceeds intended for general corporate purposes amid potential government shutdown concerns.

TMO PCVX bond offering government shutdown investment-grade debt corporate funding
Sentiment note

Announced new manufacturing agreement with Thermo Fisher for fill-finish commercial manufacturing of pneumococcal conjugate vaccines, representing potential up to $1 billion commitment

Positive GlobeNewswire Inc. • Delveinsight
Pneumococcal Infections Clinical Trial Analysis: Key Insights into Rich Pipeline Featuring 15+ Companies and 20+ Therapies | DelveInsight

The pneumococcal infection market is expected to grow steadily, driven by high global disease burden, rising antimicrobial resistance, and expanded immunization initiatives. Over 15 companies are developing 20+ pipeline therapies, with next-generation vaccines targeting broader serotype coverage.

SNY PCVX pneumococcal infections vaccine development clinical trials immunization
Sentiment note

Advancing VAX-31 vaccine through clinical trials, received FDA Breakthrough Therapy designation, demonstrated strong immune responses in Phase I/II study

Neutral The Motley Fool • Jesterai
Vaxcyte (PCVX) Q2 Loss Widens 11%

Vaxcyte reported a wider Q2 2025 net loss of $1.22 per share, driven by increased R&D and G&A expenses. The company advanced its VAX-31 vaccine program with FDA Breakthrough Therapy Designation and has $2.8 billion in cash to fund operations through mid-2028.

PCVX vaccine pneumococcal clinical trials biotechnology FDA
Sentiment note

Mixed financial performance with increased expenses, but significant progress in vaccine development and substantial cash reserves to support future research

Positive Benzinga • Vandana Singh
Vaxcyte Plans To Drop Developing One Pneumococcal Conjugate Vaccine

Vaxcyte has selected the VAX-24 Mid-dose as the basis for advancing an optimized dose formulation to a potential Phase 3 program. The company plans to initiate an infant Phase 3 study with either VAX-24 or VAX-31 pending the VAX-31 infant Phase 2 study topline data results anticipated in mid-2026.

PCVX PFE Vaxcyte pneumococcal conjugate vaccine VAX-24 VAX-31 Phase 2 Phase 3
Sentiment note

Vaxcyte has selected the VAX-24 Mid-dose as the basis for advancing to a potential Phase 3 program and plans to initiate an infant Phase 3 study with either VAX-24 or VAX-31, indicating progress in their vaccine development.

Negative GlobeNewswire Inc. • N/A
Kuehn Law Encourages Investors of Vaxcyte, Inc. to Contact Law Firm

Kuehn Law, a shareholder litigation law firm, is investigating potential self-dealing by officers and directors of Vaxcyte, Inc. Shareholders may be entitled to damages and corporate governance reforms.

PCVX Vaxcyte, Inc. shareholder litigation fiduciary duties self-dealing
Sentiment note

The article indicates that Kuehn Law is investigating potential breaches of fiduciary duties by Vaxcyte's officers and directors, which suggests potential wrongdoing or mismanagement within the company.

Positive The Motley Fool • Anthony Di Pizio
Trump and Interest Rates: The 2 Key Reasons This Vanguard ETF Could Thrive in 2025

The Vanguard Russell 2000 ETF (VTWO) could be a great investment opportunity in 2025 due to potential benefits from the incoming Trump administration's policies and further interest rate cuts from the Federal Reserve.

VTWO SFM PCVX AIT Russell 2000 index Vanguard Russell 2000 ETF Trump administration Federal Reserve
Sentiment note

The article mentions Vaxcyte, a California-based developer of vaccines, as another example of a company in the Russell 2000 index that could benefit from the Trump administration's policies.

Positive GlobeNewswire Inc. • N/A
Vaxcyte Announces Pricing of $1.3 Billion Public Offering

Vaxcyte, a vaccine innovation company, announced the pricing of a $1.3 billion public offering of common stock and pre-funded warrants. The offering is expected to close on September 6, 2024.

PCVX Vaxcyte vaccine public offering common stock pre-funded warrants
Sentiment note

The company is raising a significant amount of capital through a public offering, which suggests it has promising vaccine candidates and growth prospects.

Positive GlobeNewswire Inc. • N/A
Vaxcyte Announces Commencement of Proposed Public Offering of Common Stock and Pre-Funded Warrants

Vaxcyte, a vaccine innovation company, has announced a $1.0 billion public offering of its common stock and pre-funded warrants. The offering is subject to market conditions and will be used to fund the development of the company's vaccine candidates.

PCVX Vaxcyte public offering vaccine development
Sentiment note

The company is raising a significant amount of capital through a public offering, which suggests it has promising vaccine candidates in development and is well-positioned for future growth.

Positive Benzinga • Vandana Singh
Bacterial Infections Vaccine Developer Vaxcyte's Pneumococcal Shot Shows Promise in Mid-Stage Trial, Stock Shoots Higher

Vaxcyte's 31-valent pneumococcal conjugate vaccine candidate, VAX-31, showed promising results in a Phase 1/2 study, meeting or exceeding the immunogenicity criteria compared to Pfizer's Prevnar 20. Vaxcyte plans to initiate a Phase 3 study by mid-2025.

PCVX PFE MRK Vaxcyte pneumococcal vaccine Phase 1/2 study Prevnar 20
Sentiment note

The article reports positive results from Vaxcyte's Phase 1/2 study of its pneumococcal vaccine candidate, VAX-31, which met or exceeded the immunogenicity criteria compared to Pfizer's Prevnar 20. The company plans to advance the vaccine to a Phase 3 study, indicating progress in its development.

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