PACB
Pacific Biosciences of California, Inc. · Healthcare · Medical Devices
Last
$1.74
−$0.23 (−11.48%) 4:00 PM ET
After hours $1.74 $0.00 (0.00%) 6:59 PM ET
Prev close $1.96
Open $1.95
Day high $1.95
Day low $1.71
Volume 10,311,885
Avg vol 15,029,099
Mkt cap
$609.23M
EV/Sales
7.49
P/E ratio
-4.13
FY Revenue
$159.27M
EPS
-0.42
Gross Margin
36.38%
Div yield
0.00%
Sector
Healthcare
AI report sections
PACB
Pacific Biosciences of California, Inc.
No AI report section text found yet for this symbol.
AI summarized at 9:49 AM ET, 2026-10-05
AI summary scores
INTRADAY: 72 SWING: 77 LONG: 17
Volume vs average
Intraday (cumulative)
−17% (Below avg)
Vol/Avg: 0.83×
RSI
50.26 (Neutral)
Neutral (40–60)
MACD momentum
Intraday
-0.00 (Weak)
MACD: 0.00 Signal: 0.00
Short-Term
-0.06 (Weak)
MACD: 0.18 Signal: 0.24
Long-Term
-0.01 (Weak)
MACD: 0.29 Signal: 0.29
Intraday trend score 26.18

Latest news

PACB 12 articles Positive: 7 Neutral: 0 Negative: 5
Negative Zacks Investment Research • Zacks.Com
Pacific Biosciences of California (PACB) Declines More Than Market: Some Information for Investors

Pacific Biosciences of California (PACB) closed at $1.99, down 2.93%, underperforming the S&P 500's 1.11% loss. Despite a 52.99% monthly gain, the company faces headwinds with expected EPS of -$0.13 (down 8.33% YoY) and revenue of $37.86 million (down 1.51% YoY). The stock holds a Zacks Rank #3 (Hold) rating with steady consensus estimates.

PACB Pacific Biosciences genetic analysis technology earnings decline stock underperformance medical instruments Zacks Rank
Sentiment note

The company is expected to report declining earnings (-8.33% YoY) and declining revenue (-1.51% YoY). The stock underperformed the broader market on the trading day and holds a neutral Zacks Rank #3 (Hold) rating, indicating limited upside potential despite recent monthly gains.

Positive Zacks Investment Research • Na
PacBio Teams With TychoBio to Advance AI-Driven RNA Therapeutics

Pacific Biosciences announced a collaboration with TychoBio to generate full-length RNA sequencing data for training AI models designed to develop RNA therapies for rare diseases. TychoBio will analyze over 10,000 samples using PacBio's HiFi and Kinnex sequencing technologies to build datasets linking RNA therapy designs to their effects, with initial focus on steric blocking antisense oligonucleotides. The partnership strengthens PacBio's presence in rare disease research and could drive demand for its sequencing platforms.

PACB RNA sequencing AI-driven drug discovery rare diseases long-read sequencing therapeutic development antisense oligonucleotides
Sentiment note

Strategic partnership with TychoBio expands PacBio's presence in AI-driven therapeutic research and rare disease development. The collaboration leverages PacBio's HiFi and Kinnex technologies, potentially driving demand for sequencing platforms and consumables. Year-to-date stock performance of +12.3% outperforms industry decline of -4.9%.

Negative Zacks Investment Research • Zacks.Com
Why Pacific Biosciences of California (PACB) Dipped More Than Broader Market Today

Pacific Biosciences of California (PACB) fell 15.44% on October 8, 2026, significantly underperforming the S&P 500's 0.47% decline. Despite a strong 110.85% gain over the past month, the genetic analysis technology company faces headwinds with projected EPS of -$0.13 (down 8.33% YoY) and revenue expected at $37.86 million (down 1.51% YoY). The stock holds a Zacks Rank #3 (Hold) rating.

PACB Pacific Biosciences genetic analysis technology stock decline earnings forecast medical instruments Zacks Rank
Sentiment note

The stock experienced a significant 15.44% single-day decline, substantially worse than the broader market. Upcoming earnings projections show declining EPS (-8.33% YoY) and declining revenue (-1.51% YoY). The company maintains a Hold rating (Zacks Rank #3), indicating neutral-to-cautious analyst sentiment despite recent monthly gains.

Positive GlobeNewswire Inc. • Researchandmarkets.Com
Immunogenomics Market Size, Share, Trends, and Growth Forecast, 2026-2033 | NGS and Personalized Medicine Drive Market Toward USD 9.82 Billion at 5.97% CAGR

The global immunogenomics market is projected to grow from USD 6.32 billion in 2025 to USD 9.82 billion by 2033, expanding at a CAGR of 5.97%. Growth is driven by advancements in next-generation sequencing technologies, increasing demand for personalized medicine, and rising prevalence of immune-related disorders. Key applications include oncology, infectious disease research, vaccine development, and autoimmune disorder studies, with adoption across hospitals, diagnostic laboratories, pharmaceutical companies, and academic institutions.

TMO ILMN QGEN RHHBY immunogenomics next-generation sequencing personalized medicine cancer immunotherapy
Sentiment note

Listed as a key participant in the immunogenomics market, which is expanding due to advancements in next-generation sequencing technologies and growing personalized medicine demand.

Negative Zacks Investment Research • Zacks.Com
Pacific Biosciences of California (PACB) Rises Higher Than Market: Key Facts

Pacific Biosciences of California (PACB) stock rose 1.2% to $2.54, outperforming the S&P 500's 0.73% gain. Despite a 93.08% monthly surge, the company faces headwinds with projected EPS of -$0.13 (down 8.33% YoY) and revenue of $37.86 million (down 1.51% YoY). PACB holds a Zacks Rank of #4 (Sell) with unchanged consensus estimates over the past 30 days.

PACB genetic analysis technology earnings forecast stock performance Zacks Rank Medical sector EPS estimates
Sentiment note

Despite recent stock price appreciation, the company carries a Zacks Rank #4 (Sell) rating. Projected earnings show an 8.33% decline YoY, revenue is expected to decline 1.51% YoY, and consensus EPS estimates remain unchanged, indicating weak near-term business momentum and analyst skepticism about profitability.

Negative Zacks Investment Research • Zacks.Com
Why Pacific Biosciences of California (PACB) Outpaced the Stock Market Today

Pacific Biosciences of California (PACB) gained 2.99% on September 17, 2026, outperforming the S&P 500's 1.14% gain. The stock has climbed 5.51% over the past month. However, the company faces headwinds with projected earnings decline of 8.33% year-over-year and a Zacks Rank of #4 (Sell), indicating negative analyst sentiment despite recent price momentum.

PACB Pacific Biosciences genetic analysis technology stock performance earnings forecast Zacks Rank Medical sector
Sentiment note

Despite short-term stock price outperformance (+2.99% daily, +5.51% monthly), the company carries a Zacks Rank #4 (Sell) rating. Projected earnings are declining 8.33% year-over-year, revenue is expected to drop 1.51%, and analyst consensus estimates have remained unchanged over the past 30 days, indicating weak fundamental outlook and analyst skepticism about future performance.

Negative Zacks Investment Research • Zacks.Com
Pacific Biosciences of California (PACB) Dips More Than Broader Market: What You Should Know

Pacific Biosciences of California (PACB) declined 1.55% to $1.27, underperforming the S&P 500's 0.59% loss. Despite a 16.22% gain over the past month, the company faces headwinds with projected EPS of -$0.13 (down 8.33% YoY) and revenue of $37.86 million (down 1.51% YoY). PACB holds a Zacks Rank of #4 (Sell) with stagnant EPS projections over the past 30 days.

PACB genetic analysis technology earnings decline stock underperformance Zacks Rank Sell medical instruments industry
Sentiment note

PACB received a Zacks Rank #4 (Sell) rating with projected earnings decline of 8.33% YoY and revenue decline of 1.51% YoY. The stock underperformed broader market indices, and consensus EPS projections remained stagnant over the past 30 days, indicating weak near-term business momentum.

Positive GlobeNewswire Inc. • Bcc Research
AI Disruption Reshapes Bioinformatics: Record Investment and Breakthrough Tools Signal a New Era for Drug Discovery and Precision Medicine

Artificial intelligence is fundamentally restructuring bioinformatics, compressing drug discovery timelines and attracting billions in venture capital. AI tools like AlphaFold and generative biology platforms are delivering measurable ROI, with companies achieving 99% cost reductions in drug discovery. North America leads adoption, supported by federal programs and substantial R&D investments from established life sciences players.

ILMN TMO A BIO artificial intelligence bioinformatics drug discovery protein structure prediction
Sentiment note

Invested $135 million in R&D in 2024, demonstrating active engagement in AI bioinformatics integration and commitment to next-generation sequencing infrastructure.

Positive GlobeNewswire Inc. • Delveinsight
Global Metagenomics Sequencing Market to Register Stunning Growth at a CAGR of ~13% by 2034 | DelveInsight

The global metagenomics sequencing market is projected to grow from USD 2.5 billion in 2025 to USD 7.5 billion by 2034, driven by declining NGS costs, rising infectious disease burden, microbiome research expansion, and clinical diagnostic adoption. North America leads with 41% market share, while Asia-Pacific emerges as a major growth engine.

RHHBY TMO PACB QGEN metagenomics sequencing next-generation sequencing infectious disease diagnostics microbiome research
Sentiment note

Listed among key companies in the growing metagenomics sequencing market with long-read sequencing technology relevance

Positive GlobeNewswire Inc. • Researchandmarkets.Com
Omics-Based Clinical Trials Research Report 2026: $47.78 Bn Market Opportunities, Trends, Competitive Landscape, Strategies, and Forecasts, 2020-2025, 2025-2030F, 2035F

The omics-based clinical trials market is experiencing robust growth, expanding from $31.71 billion in 2025 to $34.49 billion in 2026 with an 8.8% CAGR, and projected to reach $47.78 billion by 2030. Growth is driven by increasing demand for personalized medicine, genomics advancements, AI-enabled patient recruitment, and biomarker-driven trial designs. North America leads the market while Asia-Pacific shows rapid expansion potential.

PFE RHHBY TMO GSK omics-based clinical trials personalized medicine genomics biomarker-driven designs
Sentiment note

Demonstrating strategic growth through partnership with A*STAR and Macrogen to launch a Singapore-based lab for high-precision genomics and personalized medicine research.

Positive GlobeNewswire Inc. • Bcc Research
Global DNA Read, Write and Edit Market to Surge to $67.7 Billion by 2030, Driven by CRISPR Advances, Genomic Diagnostics and Expanding Clinical Applications

The global DNA read, write and edit market is projected to grow from $21.4 billion in 2024 to $67.7 billion by 2030 at a 21.2% CAGR, driven by expanding clinical applications of genome editing, genomic diagnostics demand, and CRISPR-based therapeutics investment. North America leads with 43.5% market share.

ILMN TMO BEAM VRTX DNA sequencing CRISPR technology genome editing genomic diagnostics
Sentiment note

Sequencing technology leader positioned in high-growth market with expanding clinical applications and genomic diagnostics demand.

Positive GlobeNewswire Inc. • Nova One Advisor
Genomics Data Analysis Market Size to Surpass USD 28.74 Bn by 2034

The global genomics data analysis market is projected to grow from $6.85 billion in 2024 to $28.74 billion by 2034, driven by advancements in sequencing technologies, personalized medicine demand, and AI-driven analytics.

TMO A RHHBY QGEN genomics data analysis precision medicine AI
Sentiment note

Included in top companies of a market with substantial growth projections

News and sentiment labels describe article tone and are provided for research purposes only. They are not trading recommendations or forecasts.
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