Nurix Therapeutics, Inc. · Healthcare · Biotechnology
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$15.98
−$0.13 (−0.80%) 4:00 PM ET
Prev closePrevC$16.11
OpenOpen$15.90
Day highHigh$16.05
Day lowLow$15.64
VolumeVol643,138
Avg volAvgVol1,021,602
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Mkt cap
$1.64B
P/E ratio
-5.24
FY Revenue
$83.98M
EPS
-3.05
Gross Margin
100.00%
Sector
Healthcare
AI report sections
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NRIX
Nurix Therapeutics, Inc.
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Nurix Stock Is Down 6% This Past Year, but One Biotech Fund Still Boosted Its Bet By $63 Million
Redmile Group increased its stake in Nurix Therapeutics by 4.4 million shares worth $63.43 million, bringing its total position to 11.31% of its assets. Despite the stock being down 6.5% over the past year, the fund's conviction in the biotech company reflects confidence in its lead BTK degrader program entering a registrational trial with strong Phase 1 data showing 83% objective response rate.
Despite near-term stock underperformance (-6.5% YoY), the company shows positive catalysts with its lead BTK degrader entering registrational trials with strong Phase 1 efficacy data (83% response rate, 22.1 months PFS). Strong cash position ($592.9M) and major pharma partnerships support long-term potential. Redmile Group's significant $63M increase in stake signals institutional confidence in the pipeline.
PositiveBenzinga• Prnewswire
Precision Killers: Why Big Pharma is Betting Billions to Beat a $170B Patent Cliff
The precision oncology market is projected to grow from $110 billion to $225.65 billion by 2032, driven by Big Pharma's race to acquire registration-ready assets ahead of a $170 billion patent cliff through 2030. Several biotech companies are advancing promising clinical programs: Oncolytics Biotech strengthened its leadership team for pelareorep development in gastrointestinal cancers; Nurix is executing pivotal studies for its BTK degrader bexobrutideg in chronic lymphocytic leukemia; Erasca reported early clinical data for its pan-RAS molecular glue ERAS-0015; Foghorn raised $50 million for its SMARCA4-targeting program; and ORIC presented strong Phase 1b data for rinzimetostat in prostate cancer.
Advanced BTK degrader bexobrutideg into pivotal Phase 2/3 development with strong clinical data (83% objective response rate in CLL), maintains solid cash position ($663.8 million), and is executing planned 2026 milestones for global registration.
PositiveGlobeNewswire Inc.• Nurix Therapeutics
Nurix Therapeutics Presents New Data Demonstrating Durable, Deepening Responses in Phase 1 Trial of Bexobrutideg (NX-5948) in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) at the 67th American Society of Hematology (ASH) Annual Meeting & Exposition
Nurix Therapeutics reported promising Phase 1 trial results for bexobrutideg, an investigational drug for relapsed or refractory chronic lymphocytic leukemia, showing an 83% objective response rate and a median progression-free survival of 22.1 months.
Demonstrated strong clinical trial results with high objective response rate, extended progression-free survival, and favorable safety profile for their investigational drug bexobrutideg
PositiveGlobeNewswire Inc.• Nurix Therapeutics
Nurix Therapeutics Announces Webcast to Review New and Updated Data from the Phase 1 Clinical Trial of BTK Degrader Bexobrutideg (NX-5948) To Be Presented at the 67th American Society of Hematology (ASH) Annual Meeting and Exposition
Nurix Therapeutics will host a webcast on December 8, 2025, to present new clinical data on bexobrutideg (NX-5948), an investigational BTK degrader for treating chronic lymphocytic leukemia and Waldenström macroglobulinemia.
Company is presenting promising clinical trial data, expanding research into targeted protein degradation medicines, and hosting an informative webcast about their drug development progress
PositiveGlobeNewswire Inc.• Nurix Therapeutics
Nurix Therapeutics Announces Presentations at the 67th American Society of Hematology (ASH) Annual Meeting
Nurix Therapeutics will present updated clinical data on bexobrutideg, a novel BTK degrader, at the ASH Annual Meeting, showcasing results in chronic lymphocytic leukemia and Waldenström macroglobulinemia treatments.
Company is presenting promising clinical trial data for its investigational drug bexobrutideg across multiple cancer types, indicating potential therapeutic advancements
PositiveGlobeNewswire Inc.• Nurix Therapeutics, Inc.
Nurix Therapeutics Announces Closing of $250.0 Million Registered Offering of Common Stock
Nurix Therapeutics raised $250 million through a stock offering to fund clinical development of drug candidates targeting chronic lymphocytic leukemia and potential autoimmune indications.
Successfully raised significant capital ($250M) to advance clinical trials and explore new therapeutic potential, with support from multiple investors
PositiveGlobeNewswire Inc.• Nurix Therapeutics, Inc.
Nurix Initiates DAYBreak™ Pivotal Study of Bexobrutideg in Relapsed or Refractory Chronic Lymphocytic Leukemia
Nurix Therapeutics launched a pivotal Phase 2 clinical trial (DAYBreak) for bexobrutideg, a potential BTK degrader treatment for relapsed or refractory chronic lymphocytic leukemia, with plans for a Phase 3 confirmatory study in 2026.
Company is advancing a promising drug candidate with potential Accelerated Approval, transitioning to a pivotal-stage company, and demonstrating innovative drug development in targeted protein degradation
PositiveGlobeNewswire Inc.• Nurix Therapeutics
Nurix Therapeutics Reports New Clinical Data from First-in-Class Oral CBL-B Inhibitor, NX-1607, Demonstrating Single-Agent Activity Across Multiple Tumor Types at the European Society for Medical Oncology (ESMO) Congress
Nurix Therapeutics presented Phase 1a clinical data for NX-1607, a first-in-class oral CBL-B inhibitor, showing promising anti-tumor activity across multiple solid tumor types with evidence of immune activation and clinical benefits.
Demonstrated promising early-stage clinical results for novel cancer therapy, showing potential anti-tumor activity and tolerable safety profile across multiple tumor types
PositiveGlobeNewswire Inc.• Delveinsight
Non-Hodgkin’s Lymphoma Market Forecast to Surge with Growing Adoption of Targeted and Cell-Based Therapies | DelveInsight
The non-Hodgkin's lymphoma market is expected to grow significantly between 2025-2034, driven by increasing incidence, advancements in targeted therapies, emerging treatments, and improved early detection efforts.
Announced positive clinical data for bexobrutideg (NX-5948) in treating relapsed/refractory B-cell malignancies
NeutralGlobeNewswire Inc.• Delveinsight
Waldenstrom Macroglobulinemia Market Sees Surging Demand Across the 7MM Amid BTK Inhibitor Advancements | DelveInsight
The Waldenstrom macroglobulinemia market is experiencing steady growth driven by advances in targeted therapies, particularly BTK inhibitors. Rising awareness, improved diagnostics, and increasing clinical trials are propelling market expansion, with several emerging drugs showing promise in treating this rare lymphoma.
Developing NX-5948, which received FDA orphan drug designation for Waldenstrom macroglobulinemia treatment
PositiveGlobeNewswire Inc.• N/A
Nurix Therapeutics to Host a Webcast Conference Call to Discuss Data from the Ongoing Phase 1 Clinical Trial of Bexobrutideg (NX-5948) Being Presented at the 30th European Hematology Association Congress (EHA2025)
Nurix Therapeutics will host a webcast conference call to discuss new data from the ongoing Phase 1 clinical trial of bexobrutideg (NX-5948) that will be presented at the European Hematology Association Congress.
The article discusses Nurix Therapeutics hosting a webcast conference call to present new data from the ongoing Phase 1 clinical trial of their drug candidate bexobrutideg, which suggests the company is making progress in its drug development efforts.
NeutralBenzinga• Vandana Singh
Sanofi Expands Rare Immunology Portfolio With Blueprint Buyout
Sanofi agreed to acquire Blueprint Medicines for $9.5 billion, including the rare immunology disease medicine Ayvakit and a promising pipeline. The deal will expand Sanofi's rare and immunology portfolios.
Nurix Therapeutics licensed its STAT6 program to Sanofi, which is a separate deal from the Blueprint Medicines acquisition.
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