MIRM
Mirum Pharmaceuticals, Inc. · Healthcare · Biotechnology
At close
$95.36
−$0.50 (−0.52%) Close
Pre-market $95.86 +$0.50 (+0.52%) 8:08 AM ET
Prev close $95.86
Open $95.75
Day high $95.75
Day low $95.36
Volume 636
Avg vol 920,996
Mkt cap
$5.78B
P/E ratio
-194.61
FY Revenue
$521.31M
EPS
-0.49
Gross Margin
80.77%
Sector
Healthcare
AI report sections
MIRM
Mirum Pharmaceuticals, Inc.
Mirum Pharmaceuticals shows strong upward price momentum with the stock near its 52-week high and well above key moving averages, supported by multiple bullish technical signals. Fundamentally, the company combines high gross margins, improving profitability metrics, and positive free cash flow with ongoing GAAP losses and a sizeable long-term debt load. Short interest is elevated with high days-to-cover and a high short-volume ratio, indicating a notable level of positioning against the stock despite generally positive recent news flow.
AI summarized at 2:25 PM ET, 2025-12-22
AI summary scores
INTRADAY: 68 SWING: 74 LONG: 71
Volume vs average
Intraday (cumulative)
−56% (Below avg)
Vol/Avg: 0.44×
RSI
54.61 (Neutral)
Neutral (40–60)
MACD momentum
Intraday
-0.03 (Weak)
MACD: 0.10 Signal: 0.14
Short-Term
+0.68 (Strong)
MACD: 0.97 Signal: 0.30
Long-Term
+0.71 (Strong)
MACD: 0.10 Signal: -0.61
Intraday trend score 55.16

Latest news

MIRM 12 articles Positive: 2 Neutral: 3 Negative: 0
Neutral The Motley Fool • Jonathan Ponciano
Biotech Stock Up 372% Gets Sold as New Pick Rises 40% in 2026

Boone Capital Management liquidated its entire $13.57 million stake in Cogent Biosciences (945,042 shares) in Q4 2026, despite the stock surging 372% over the past year. The fund reallocated capital to earlier-stage biotech opportunities like TYRA, which has gained 40% in 2026, suggesting a strategic shift toward higher-risk, higher-upside clinical-stage investments.

COGT TYRA MDT MIRM biotech portfolio reallocation clinical-stage precision medicine
Sentiment note

Listed as a top holding (10.4% of AUM, $33.27M) in the fund's portfolio, representing a significant established position.

Neutral GlobeNewswire Inc. • Na
XOMA Royalty Reports 2025 Financial Results and Highlights Recent Business Achievements

XOMA Royalty Corporation reported over $50 million in cash receipts for 2025, with royalties up 68% year-over-year. The company added 22 assets to its portfolio, completed seven acquisitions generating $11.7 million in non-dilutive capital, and repurchased 648,048 shares for $16 million. Key 2026 catalysts include Phase 2b/3 data readouts and potential EMA regulatory decisions on commercial assets OJEMDA and MIPLYFFA.

DAWN ZVRA RZLT GOSS biotech royalty aggregator cash receipts portfolio expansion acquisitions
Sentiment note

Volixibat Phase 2b VISTAS study in PSC expected to report topline data in Q2 2026 and Phase 3 VANTAGE study in PBC expected to complete enrollment in H2 2026, representing upcoming catalysts with uncertain outcomes.

Neutral The Motley Fool • Prosper Junior Bakiny
Is Mirum Pharmaceuticals on a Strong Path to Profitability?

Mirum Pharmaceuticals showed profitability in Q3 2025 and strong revenue growth of 56.8% year-over-year through nine months. However, the company faces headwinds including slowing sales growth guidance for 2026 (23.1% vs 54.4% in 2025) and near-term profitability challenges from the $620 million Bluejay Therapeutics acquisition. While the stock has doubled over 12 months, analysts suggest profitability may take several more years to achieve consistently.

MIRM biotech profitability revenue growth acquisition rare diseases clinical catalysts sales guidance
Sentiment note

Mixed signals: positive Q3 profitability and strong YoY revenue growth (56.8%), but offset by decelerating 2026 sales growth guidance (23.1%), acquisition-related costs from Bluejay Therapeutics deal, and analyst view that consistent profitability remains years away. Stock momentum is strong but upside appears limited with elevated risk.

Positive The Motley Fool • Jonathan Ponciano
Why a Top Biotech Holder Sold 115,000 Mirum Shares but Still Ended Up With $185 Million on the Line

Eventide Asset Management sold 114,922 shares of Mirum Pharmaceuticals in Q3, but the position's value increased by approximately $50.70 million to $184.92 million due to the stock's 89% surge over the past year. The share reduction appears to be portfolio management rather than a loss of confidence, as Mirum posted strong Q3 revenue growth of 47% and raised full-year guidance, with the company now representing the fund's second-largest equity holding.

MIRM GH XMTR biotech Mirum Pharmaceuticals institutional investment rare diseases portfolio management
Sentiment note

Strong Q3 revenue growth of 47%, raised full-year guidance to $500-510 million, stock up 89% over the past year, solid cash position of $378 million, and continued strength in LIVMARLI sales indicate strong commercial traction and business momentum.

Positive The Motley Fool • Keith Speights
Prediction: This Stock Has Soared Nearly 70% in 2025 and Will Be an Even Bigger Winner in 2026

Mirum Pharmaceuticals has seen nearly 70% stock growth in 2025, with its flagship drug Livmarli driving sales and potential for continued expansion in 2026, supported by promising pipeline candidates volixibat and MRM-3379.

MIRM biotech pharmaceuticals drug development stock prediction Livmarli
Sentiment note

Strong sales growth for Livmarli (56% year-over-year), potential billion-dollar drug, promising pipeline candidates, and expected continued momentum in 2026

Unknown Zacks Investment Research • Zacks Equity Research
Mirum (MIRM) Soars on Interim Data From Liver Disease Studies

Mirum (MIRM) posts positive interim data from two phase IIb studies evaluating volixibat in patients with primary biliary cholangitis and primary sclerosing cholangitis. Stock rises.

MIRM RAPT ALGS ACRV
Unknown Zacks Investment Research • Zacks Equity Research
Mirum Pharmaceuticals (MIRM) Soars 27.3%: Is Further Upside Left in the Stock?

Mirum Pharmaceuticals (MIRM) saw its shares surge in the last session with trading volume being higher than average. The latest trend in earnings estimate revisions may not translate into further price increase in the near term.

MIRM BMRN
Unknown Zacks Investment Research • Zacks Equity Research
Why Is Mirum Pharmaceuticals (MIRM) Down 3.4% Since Last Earnings Report?

Mirum Pharmaceuticals (MIRM) reported earnings 30 days ago. What's next for the stock? We take a look at earnings estimates for some clues.

MIRM AXSM
Unknown Zacks Investment Research • Zacks Equity Research
Mirum's (MIRM) Livmarli Aids Sales but Overdependence Concerns

Mirum's (MIRM) lead drug, Livmarli, continues to generate steady sales. The recent label expansion of the drug should drive sales further. However, overdependence on Livmarli for revenues is a concern.

NERV MRNS KRYS MIRM
Unknown Zacks Investment Research • Zacks Equity Research
Mirum's (MIRM) Q1 Earnings & Revenues Fall Shy of Estimates

Mirum's (MIRM) earnings and revenues miss estimates in the first quarter of 2024. Livmarli drives year-over-year sales.

LGND ENTX MIRM THRD
Unknown Benzinga • Benzinga Insights
Analyst Ratings For Mirum Pharmaceuticals

In the preceding three months, 10 analysts have released ratings for Mirum Pharmaceuticals (NASDAQ:MIRM), presenting a wide array of perspectives from bullish to bearish. The table below provides a snapshot of their recent ratings, showcasing how sentiments have evolved over the past 30 days and comparing them to the preceding months. Bullish Somewhat Bullish Indifferent Somewhat Bearish Bearish Total Ratings 5 5 0 0 0 Last 30D 1 0 0 0 0 1M Ago 1 0 0 0 0 2M Ago 2 2 0 0 0 3M Ago 1 3 0 0 0 Analysts provide deeper insights through their assessments of 12-month price targets, revealing an average target of $52.6, a high estimate of $72.00, and a low estimate of $35.00. This current average represents a 1.29% decrease from the previous average price target of $53.29. Investigating Analyst Ratings: An Elaborate Study A comprehensive examination of how financial experts perceive Mirum Pharmaceuticals is derived from recent analyst actions. The following is a detailed summary of key analysts, their recent evaluations, and adjustments to ratings and price targets. Analyst Analyst Firm Action Taken Rating Current Price Target Prior Price Target Ed Arce HC Wainwright & Co. Maintains Buy $58.00 - Dae Gon Ha Stifel Announces Buy $48.00 - Ed Arce HC Wainwright & Co. Maintains Buy $58.00 $58.00 Mani Foroohar Leerink Partners Lowers Outperform $43.00 $44.00 Jonathan Wolleben JMP Securities Raises Outperform $72.00 $69.00 Ed Arce HC Wainwright & Co. Raises Buy $58.00 $45.00 Josh Schimmer Cantor Fitzgerald Raises Overweight $40.00 $35.00 Ed Arce HC Wainwright & Co. Lowers Buy $45.00 $58.00 Jonathan Wolleben JMP Securities Raises Market Outperform $69.00 $64.00 Josh Schimmer Cantor Fitzgerald Maintains Overweight $35.00 - Key Insights: Action Taken: Analysts respond to changes in market conditions and company performance, frequently updating their recommendations. Whether they 'Maintain', 'Raise' or 'Lower' their stance, it reflects their reaction to ...Full story available on Benzinga.com

MIRM Analyst Ratings
Unknown Zacks Investment Research • Zacks Equity Research
Halozyme Therapeutics (HALO) Earnings Expected to Grow: Should You Buy?

Halozyme Therapeutics (HALO) doesn't possess the right combination of the two key ingredients for a likely earnings beat in its upcoming report. Get prepared with the key expectations.

HALO MIRM
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