KRYS
Krystal Biotech, Inc. · Healthcare · Biotechnology
Last
$316.54
−$13.47 (−4.08%) 4:00 PM ET
After hours $316.60 +$0.06 (+0.02%) 1:17 AM ET
Prev close $330.00
Open $330.06
Day high $332.36
Day low $315.34
Volume 225,801
Avg vol 285,178
Mkt cap
$9.77B
EV/Sales
21.20
P/E ratio
40.45
FY Revenue
$440.48M
EPS
8.16
Gross Margin
94.64%
Div yield
0.00%
Sector
Healthcare
AI report sections
KRYS
Krystal Biotech, Inc.
KRYS shows positive multi-month price momentum and constructive daily technical readings, with the latest close remaining above short-term moving averages and VWAP. Financial results show high margins, positive free cash flow, and no long-term debt, while elevated earnings and cash-flow valuation multiples, meaningful short interest, and proximity to the 52-week high frame the principal offsetting factors.
AI summarized at 8:12 PM ET, 2026-09-02
AI summary scores
INTRADAY: 65 SWING: 73 LONG: 59
Volume vs average
Intraday (cumulative)
+11% (Above avg)
Vol/Avg: 1.11×
RSI
46.73 (Neutral)
Neutral (40–60)
MACD momentum
Intraday
+0.22 (Strong)
MACD: -0.10 Signal: -0.32
Short-Term
-0.00 (Weak)
MACD: -4.02 Signal: -4.02
Long-Term
-0.87 (Weak)
MACD: -3.67 Signal: -2.81
Intraday trend score 35.29

Latest news

KRYS 12 articles Positive: 6 Neutral: 6 Negative: 0
Positive Zacks Investment Research • Na
KRYS Reports Positive Early Data for KB113 in Gorlin Syndrome

Krystal Biotech announced positive pilot study results for KB113, an investigational immunotherapy for basal cell carcinomas in Gorlin syndrome patients. The treatment showed clinical regression in 83.1% of assessed lesions across three patients, including 85.1% regression in non-injected lesions suggesting systemic immune activity. KB113 was well tolerated, and the company has begun FDA discussions on advanced clinical development.

KRYS HOWL ARVN HALO KB113 basal cell carcinoma Gorlin syndrome immunotherapy
Sentiment note

Positive clinical data showing 83.1% regression rate in BCC lesions, evidence of systemic immune-mediated activity, good tolerability, and initiation of FDA discussions for advanced development. Year-to-date stock performance up 33.9%. However, limited by small sample size (3 patients) and early-stage development.

Positive GlobeNewswire Inc. • Not Specified
Krystal Biotech to Present at 2026 Cantor Global Healthcare Conference

Krystal Biotech announced its participation in the 2026 Cantor Global Healthcare Conference on September 10, 2026, in New York. Management will participate in a fireside chat at 3:55 pm ET and host investor meetings. The company reported strong Q2 2026 results with $119.2 million in VYJUVEK global revenue and $965.9 million in cumulative revenue since launch, with plans for European expansions and multiple clinical data readouts expected in the second half of 2026.

KRYS Krystal Biotech VYJUVEK gene therapy dystrophic epidermolysis bullosa financial results clinical pipeline European expansion
Sentiment note

The company demonstrates strong commercial performance with $119.2 million in Q2 revenue and nearly $1 billion in cumulative VYJUVEK sales since launch. Positive indicators include planned European market expansions (Spain and Italy), multiple clinical data readouts expected in H2 2026, and active investor engagement at major healthcare conferences, suggesting confidence in pipeline advancement and market growth.

Neutral Zacks Investment Research • Zacks.Com
Krystal Biotech (KRYS) Up 12% Since Last Earnings Report: Can It Continue?

Krystal Biotech shares have gained 12% since its last earnings report, outperforming the S&P 500. The company beat Q2 2026 earnings estimates with EPS of $1.79 vs. consensus of $1.70, and revenues of $119.2 million from Vyjuvek sales grew 24% year-over-year. Despite upward estimate revisions, the stock holds a Zacks Rank #3 (Hold) with an overall VGM Score of D, suggesting in-line returns ahead.

KRYS AZN earnings report biotech revenue growth Vyjuvek stock performance estimate revisions
Sentiment note

While the company beat earnings estimates and showed strong revenue growth of 24% YoY with a 95% gross margin, the Zacks Rank #3 (Hold) rating and poor Momentum Score (F) suggest limited upside potential. The overall VGM Score of D indicates the stock is not compelling across growth, value, or momentum strategies, warranting a neutral outlook despite recent positive performance.

Positive GlobeNewswire Inc. • Na
Krystal Biotech to Report Second Quarter 2026 Financial Results on August 3, 2026

Krystal Biotech announced it will report its second quarter 2026 financial results on August 3, 2026, with a conference call and webcast at 8:30 am ET. The company is a commercial-stage biotechnology firm focused on genetic medicines, with VYJUVEK® as its first commercial product—the first redosable gene therapy approved in the United States, Europe, and Japan for treating dystrophic epidermolysis bullosa.

KRYS financial results Q2 2026 gene therapy VYJUVEK® dystrophic epidermolysis bullosa genetic medicines biotechnology
Sentiment note

The company is advancing its commercial-stage operations with a first-in-class approved product (VYJUVEK®) that has received regulatory approval in multiple major markets (US, EU, Japan, UK). The announcement of financial results reporting and continued pipeline advancement indicates business momentum and investor engagement.

Neutral The Motley Fool • Eric Volkman
Why Tutor Perini Stock Trounced the Market on Tuesday

Tutor Perini stock surged nearly 8% on Tuesday following news that it will be added to the S&P SmallCap 600 index. The construction company replaces Krystal Biotech in the index, which is itself moving up to the S&P MidCap 400 to fill the vacancy left by Taylor Morrison Home's acquisition by Berkshire Hathaway. The gain is primarily attributed to the 'index effect,' where index funds automatically purchase newly added constituents, though this has little impact on the company's fundamentals.

TPC KRYS TMHC BRK.A index inclusion S&P SmallCap 600 construction index effect
Sentiment note

Moving up from S&P SmallCap 600 to S&P MidCap 400 is typically positive, but the article does not discuss specific impact on this company.

Positive The Motley Fool • Prosper Junior Bakiny
3 Soaring Stocks That May Have More Upside Ahead

The article highlights three biotech and semiconductor stocks that have more than doubled in the past 12 months but may have further upside potential. Abivax is advancing obefazimod for ulcerative colitis with strong clinical results. Krystal Biotech is generating strong revenue growth from its approved DEB treatment Vyjuvek with significant market expansion opportunities. Marvell Technology is capitalizing on AI infrastructure spending demand for custom chips as an alternative to Nvidia's GPUs.

ABVX KRYS MRVL NVDA biotech stocks semiconductor stocks AI chips clinical trials
Sentiment note

Strong financial performance with 32% revenue growth and 56.5% net profit growth in Q1. Only approved DEB treatment with significant untapped market potential (1,300+ patients in key markets vs. 90 currently prescribed). Deep pipeline provides additional growth catalysts over next five years.

Positive The Motley Fool • Prosper Junior Bakiny
These 3 Stocks Have Crushed the Market This Year. Here's Why There Is More Upside Ahead

Three stocks—Moderna, Krystal Biotech, and AMD—have significantly outperformed the S&P 500 this year and are positioned for continued growth. Moderna is advancing toward approvals for its influenza and norovirus vaccines plus cancer vaccine candidates. Krystal Biotech's gene therapy Vyjuvek for rare skin disease is generating strong earnings with expansion opportunities. AMD is capitalizing on AI growth through its server CPU leadership and gaining market share from Intel.

MRNA KRYS AMD INTC stock market performance biotech stocks vaccine development gene therapy
Sentiment note

Vyjuvek gene therapy is the first FDA-approved treatment for dystrophic epidermolysis bullosa with rapidly growing revenue and 11-quarter earnings streak. Large addressable market remains with European expansion and multiple pipeline candidates expected to generate clinical data.

Positive GlobeNewswire Inc. • Na
Krystal Biotech to Present at Upcoming Scientific Conferences

Krystal Biotech announced it will present on multiple gene therapy programs at scientific conferences in May and June 2026, including presentations on KB409/KB410 for primary ciliary dyskinesia at ASGCT, interim CORAL-1 trial results for KB407 in cystic fibrosis at ATS, and KB707 immunotherapy data at ASCO.

KRYS gene therapy clinical trials scientific conferences genetic medicines cystic fibrosis primary ciliary dyskinesia non-small cell lung cancer
Sentiment note

The company is advancing multiple clinical programs across different therapeutic areas and presenting interim/ongoing trial results at major scientific conferences, demonstrating pipeline progress and clinical validation of its gene therapy platform. Active presentation schedule at prestigious conferences indicates advancement in drug development.

Neutral The Motley Fool • Prosper Junior Bakiny
Is Vertex Pharmaceuticals' Empire in Trouble?

Vertex Pharmaceuticals faces potential competition from newer cystic fibrosis drugs like Krystal Biotech's KB407 gene therapy, which could work for all CF patients versus Vertex's limited mutation coverage. However, the company's core franchise appears safe through the late 2030s due to patent exclusivity, and Vertex is actively diversifying its pipeline with approvals in gene editing and other therapeutic areas.

VRTX KRYS cystic fibrosis gene therapy patent exclusivity pipeline diversification biotech competition gene editing
Sentiment note

While Krystal's KB407 gene therapy shows promise with positive phase 1 results and potential to treat all CF patients, it remains in early development stages. The article acknowledges that developing CF medicines has proven challenging and no competitor has successfully challenged Vertex yet, suggesting significant hurdles remain before commercialization.

Neutral The Motley Fool • Jonathan Ponciano
What to Know About This Obesity Drug Developer That Just Drew a New $7 Million Investment

ACT Capital Management invested $7.25 million in Viking Therapeutics, acquiring 206,100 shares. Viking, a clinical-stage biotech company, is developing obesity and metabolic disorder treatments, with its lead candidate VK2735 showing promising Phase 2 results of up to 14.7% weight reduction. The company has $706 million in cash runway and is advancing multiple clinical programs including Phase 3 trials.

VKTX CVX KRYS ABVX obesity drugs clinical-stage biotech GLP-1 pathway metabolic disorders
Sentiment note

Mentioned as ACT Capital's top holding and as part of their biotech investment strategy; no specific company news or analysis provided.

Neutral The Motley Fool • Jonathan Ponciano
Nurix Stock Is Down 6% This Past Year, but One Biotech Fund Still Boosted Its Bet By $63 Million

Redmile Group increased its stake in Nurix Therapeutics by 4.4 million shares worth $63.43 million, bringing its total position to 11.31% of its assets. Despite the stock being down 6.5% over the past year, the fund's conviction in the biotech company reflects confidence in its lead BTK degrader program entering a registrational trial with strong Phase 1 data showing 83% objective response rate.

NRIX KRYS biotech investment Nurix Therapeutics Redmile Group BTK degrader clinical trial cancer therapy
Sentiment note

Mentioned as Redmile Group's second-largest holding (12.3% of AUM, $167.08M) and as a position held by The Motley Fool. No specific news or developments mentioned in the article.

Neutral The Motley Fool • Josh Kohn-Lindquist
Stock Market Today, Feb. 18: ImmunityBio Soars After EU Approves ANKTIVA for Bladder Cancer

ImmunityBio stock surged 41.36% on Feb. 18, 2026, after the European Commission granted conditional marketing authorization for its Anktiva immunotherapy to treat bladder cancer. The approval expands access to over 30 new countries and positions the drug for accelerated sales growth. Despite the positive news, the stock remains volatile and heavily dependent on Anktiva's continued success.

IBRX IOVA KRYS ImmunityBio Anktiva bladder cancer EU approval immunotherapy
Sentiment note

Mentioned as an industry peer with a slight decline of 1.58%, showing minimal market movement on this trading day.

News and sentiment labels describe article tone and are provided for research purposes only. They are not trading recommendations or forecasts.
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