Although U.S. stocks closed mixed on Tuesday, there were a few notable insider trades. When insiders purchase shares, it indicates their confidence in the company's prospects or that they view the stock as a bargain. Either way, this signals an opportunity to go long on the stock. Insider purchases should not be taken as the only indicator for making an investment or trading decision. At best, it can lend conviction to a buying decision. Below is a look at a few recent notable insider purchases. For more, check out Benzinga's insider ...

Gainers Elys Game Technology, Corp. (NASDAQ: ELYS) shares jumped 147% to $0.4312. Elys Game Technology and Cloakbook DC have been granted license to open sportsbook in Washington, D.C. 180 Life Sciences Corp. (NASDAQ: ATNF) climbed 71% to $2.12. 180 Life Sciences announced closing of $6 million registered direct offering priced at-the-market under Nasdaq rules. Neptune Wellness Solutions Inc. (NASDAQ: NEPT) shares jumped 57.7% to $0.4180 on heavy volume. Lanvin Group Holdings Limited (NYSE: LANV) shares gained 50.6% to $0.4180. HTG Molecular Diagnostics, Inc. (NASDAQ: HTGM) shares gained 28.9% to $3.9971. HTG Molecular Diagnostics announced closing of a $10 million public offering. Kaival Brands Innovations Group, Inc. (NASDAQ: KAVL) climbed 24% to $0.97. Innate Pharma S.A. (NASDAQ: IPHA) gained 19.8% to $3.3664. Innate Pharma and Sanofi recently announced an expansion of their collaboration for natural killer cell therapeutics in oncology. Innate will receive a €25 million upfront payment. Pagaya Technologies Ltd. (NASDAQ: PGY) climbed 18% to $0.9882 after gaining 10% on Friday. Renren Inc. (NYSE: RENN) gained 18% to $1.64. KalVista Pharmaceuticals, Inc. (NASDAQ: KALV) jumped 18% to $6.03. KalVista Pharmaceuticals reported a $58 million registered direct offering. Connexa Sports Technologies Inc. (NASDAQ: CNXA) rose 16% to $0.29. Soleno Therapeutics, Inc. (NASDAQ: SLNO) jumped 15.5% to $1.7098. Grove Collaborative Holdings, Inc. (NYSE: GROV) rose 14.4% to $0.2750 after gaining over 4% on Friday. PaxMedica, Inc. (NASDAQ: PXMD) gained 14.2% to $1.5999. Global Blue Group Holding AG (NYSE: GB) jumped 13.8% to $4.5650. AMC Entertainment Holdings, Inc. (NYSE: APE) rose 13.3% to $1.9597. AMC recently announced it would sell APE units to Antara Capital at an average price of $0.66. Scienjoy Holding Corporation (NASDAQ: SJ) gained 13.3% to $1.92. Scienjoy Holding recently reported interim nine months ended Sept. 30, 2022 ...