DNTH
Dianthus Therapeutics, Inc. · Healthcare · Biotechnology
Last
$92.35
−$0.56 (−0.60%) 3:29 PM ET
Prev close $92.90
Open $93.54
Day high $94.33
Day low $91.27
Volume 326,988
Avg vol 1,339,959
Mkt cap
$5.06B
P/E ratio
-22.04
FY Revenue
$2.04M
EPS
-4.19
Gross Margin
100.00%
Sector
Healthcare
AI report sections
DNTH
Dianthus Therapeutics, Inc.
Dianthus Therapeutics trades near its 52-week high after triple-digit 6–12 month price appreciation, with price currently above key moving averages and volatility elevated. Technical indicators and pattern signals point to bullish momentum, while fundamentals show substantial operating losses, negative free cash flow, and declining revenue typical of a clinical-stage biotech. Short interest is relatively high with an elevated days-to-cover and short volume ratio, and recent news tone has been broadly constructive around the therapeutic area rather than company-specific financial improvements.
AI summarized at 1:08 AM ET, 2026-01-15
AI summary scores
INTRADAY: 72 SWING: 78 LONG: 38
Volume vs average
Intraday (cumulative)
−38% (Below avg)
Vol/Avg: 0.62×
RSI
69.36 (Strong)
Strong (60–70)
MACD momentum
Intraday
+0.02 (Strong)
MACD: 0.03 Signal: 0.01
Short-Term
+0.11 (Strong)
MACD: 6.31 Signal: 6.20
Long-Term
+0.46 (Strong)
MACD: 11.18 Signal: 10.72
Intraday trend score 46.20

Latest news

DNTH 12 articles Positive: 7 Neutral: 5 Negative: 0
Neutral The Motley Fool • Pamela Kock
Dianthus Therapeutics CFO Sells $9.5 Million in Stock

Ryan Savitz, CFO of Dianthus Therapeutics, sold 114,367 shares worth $9.49 million on March 31, 2026, exercising stock options and liquidating his entire direct common stock holdings. The sale occurred under a Rule 10b5-1 plan following the company's impressive 402% stock price gain over the past year. Savitz retains 90,399 stock options, and the company's lead candidate DNTH103 is on track for phase 3 trials mid-2026.

DNTH insider selling stock options biotech monoclonal antibody clinical trials Rule 10b5-1 plan gain realization
Sentiment note

While the 402% stock price gain is positive, the CFO's complete liquidation of direct holdings raises some caution despite being under a prearranged plan. The company's lead candidate shows promise with phase 3 trials expected mid-2026, but biotech outcomes remain uncertain and insider selling can signal profit-taking rather than confidence.

Positive GlobeNewswire Inc. • Na
Dianthus Therapeutics, Inc. Announces Pricing of Upsized $625 Million Underwritten Public Offering

Dianthus Therapeutics announced the pricing of an upsized underwritten public offering of 7.3 million shares at $81.00 per share and pre-funded warrants, generating approximately $625 million in gross proceeds. The company plans to use the funds to advance clinical and preclinical development activities, commercial readiness, and general corporate purposes. The offering is expected to close on March 12, 2026.

DNTH public offering biotech capital raise autoimmune diseases clinical-stage equity offering underwriting
Sentiment note

The company successfully priced an upsized offering at $81 per share, raising $625 million in gross proceeds. This demonstrates strong investor demand and provides substantial capital to advance the company's clinical pipeline, including the Phase 3 CAPTIVATE CIDP trial which achieved early GO decision criteria. The successful capital raise supports the company's development of therapies for severe autoimmune diseases.

Positive GlobeNewswire Inc. • Na
Dianthus Therapeutics to Host Conference Call and Webcast to Discuss the Interim Responder Analysis Results of the Phase 3 Captivate Trial of Claseprubart in Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Dianthus Therapeutics announced a conference call and webcast scheduled for March 9, 2026 to discuss interim responder analysis results from Part A of the Phase 3 CAPTIVATE trial evaluating claseprubart for Chronic Inflammatory Demyelinating Polyneuropathy (CIDP). The clinical-stage biotech company is presenting data on its investigational therapy for severe autoimmune diseases.

DNTH Phase 3 trial CAPTIVATE claseprubart CIDP interim analysis autoimmune disease clinical-stage biotech
Sentiment note

The company is presenting interim responder analysis results from a Phase 3 trial, which represents progress in clinical development. The announcement of trial results typically indicates advancement in the drug development pipeline, which is generally viewed positively by investors and stakeholders in the biotech sector.

Positive GlobeNewswire Inc. • Delveinsight
Generalized Myasthenia Gravis Market Outlook Shows Strong Momentum During the Forecast Period (2025–2034) Driven by Novel Immunotherapies | DelveInsight

The generalized myasthenia gravis (gMG) market is expected to grow significantly through 2034, driven by novel immunotherapies including FABHALTA (iptacopan) from Novartis, Descartes-08 from Cartesian Therapeutics, and Claseprubart from Dianthus Therapeutics. The 7MM had approximately 205,000 prevalent gMG cases in 2024, with increasing incidence projected. These emerging therapies represent a shift toward mechanism-driven treatments targeting refractory disease and improving long-term disease control.

NVS RNAC DNTH AZN generalized myasthenia gravis immunotherapy complement inhibitors FcRn antagonists
Sentiment note

Claseprubart (DNTH103) showed positive Phase II MaGic trial results with rapid, statistically significant improvements across key gMG endpoints and favorable tolerability, positioning it as a next-generation anti-FcRn monoclonal antibody.

Neutral The Motley Fool • Sarah Sidlow
Dianthus CFO Sells 20,000 Shares for $903,600 After Massive Year-End Run

Dianthus Therapeutics CFO Ryan Savitz sold 20,000 shares worth $903,600 on December 4, 2025, completely eliminating his direct equity holdings. The sale was executed through exercise and immediate sale of vested stock options at a weighted average price of $45.18 per share. Despite the insider selling, the stock has retreated from its 52-week high of $45.45 but remains around $38, with analyst estimates suggesting a one-year target of $63.

DNTH insider selling stock options biotech clinical-stage company monoclonal antibodies autoimmune diseases SEC Form 4 filing
Sentiment note

The CFO's complete liquidation of direct holdings could signal reduced confidence, but the transaction is characterized as a routine exercise-and-sell of vested options rather than discretionary open-market selling. The company's strong 81% one-year price appreciation, recent $288 million capital raise, and promising clinical trial results in Q3 provide positive fundamentals that offset insider selling concerns. The stock remains well-positioned with analyst price targets of $63.

Positive GlobeNewswire Inc. • Not Specified
Dianthus Therapeutics To Participate in the 44th Annual J.P. Morgan Healthcare Conference

Dianthus Therapeutics, a clinical-stage biotech company focused on severe autoimmune diseases, announced its participation in the 44th Annual J.P. Morgan Healthcare Conference on January 12, 2026. CEO Marino Garcia will present a corporate overview and meet with investors. The company is also advancing its lead candidate LBL-047 (DNTH212), a bifunctional fusion protein for systemic lupus erythematosus, into Phase 1 trials.

DNTH biotech autoimmune diseases clinical-stage J.P. Morgan Healthcare Conference Phase 1 trial systemic lupus erythematosus bifunctional fusion protein
Sentiment note

The company is advancing its pipeline with Phase 1 trial initiation for a lead candidate and securing speaking opportunities at a major industry conference, demonstrating progress and investor engagement in the competitive biotech space.

Positive GlobeNewswire Inc. • Dianthus Therapeutics
Dianthus Therapeutics Highlights New Claseprubart Data Presented During 2025 AANEM Annual Meeting

Dianthus Therapeutics reported successful Phase 2 trial results for claseprubart in generalized Myasthenia Gravis, demonstrating promising treatment effects and announcing plans for a Phase 3 trial in 2026.

DNTH Myasthenia Gravis Claseprubart Phase 2 trial Complement inhibition Autoimmune disease
Sentiment note

Presented successful Phase 2 trial data, demonstrated treatment potential, and outlined clear plans for Phase 3 clinical trial with promising preclinical insights

Positive GlobeNewswire Inc. • Dianthus Therapeutics
Dianthus Therapeutics Announces Exclusive License Agreement with Leads Biolabs for DNTH212, a First and Potentially Best-In-Class, Phase 1 Ready Bifunctional BDCA2 & BAFF/APRIL Inhibitor for Severe Autoimmune Diseases

Dianthus Therapeutics has entered an exclusive licensing agreement with Leads Biolabs for DNTH212, a bifunctional fusion protein targeting autoimmune diseases. The agreement involves up to $38 million in initial payments and potential milestone payments up to $962 million, with Dianthus gaining global rights outside Greater China.

DNTH autoimmune diseases licensing agreement bifunctional fusion protein BDCA2 BAFF/APRIL inhibitor
Sentiment note

Expanded pipeline with promising new drug candidate, secured global licensing rights, maintained strong cash position of ~$525 million

Neutral GlobeNewswire Inc. • Jennifer Davis Ruff
Dianthus Therapeutics, Inc. Announces Pricing of Upsized $251 Million Underwritten Public Offering

Dianthus Therapeutics is conducting a public offering of 6,487,879 common stock shares and pre-funded warrants, expecting to raise approximately $251 million to support preclinical and clinical development activities.

DNTH public offering biotechnology stock financing clinical development
Sentiment note

The company is raising capital through a standard public offering to fund ongoing research and development, which is a typical financing strategy for clinical-stage biotechnology companies

Neutral GlobeNewswire Inc. • Jennifer Davis Ruff
Dianthus Therapeutics, Inc. Announces Proposed $150 Million Underwritten Public Offering

Dianthus Therapeutics plans to raise $150 million through a public offering of common stock or pre-funded warrants, with potential additional $22.5 million from underwriters. Proceeds will support preclinical and clinical development activities.

DNTH JEF EVR SF public offering biotechnology financing clinical development
Sentiment note

The company is seeking standard financing to support ongoing research and development, which is a typical strategic move for clinical-stage biotechnology companies

Neutral GlobeNewswire Inc. • Jennifer Davis Ruff
Dianthus Therapeutics to Host Conference Call and Webcast to Discuss Results from Phase 2 MaGic Trial of Claseprubart (DNTH103) in Generalized Myasthenia Gravis

Dianthus Therapeutics will host a conference call to discuss Phase 2 MaGic trial results for claseprubart (DNTH103) in treating generalized Myasthenia Gravis on September 8, 2025.

DNTH Myasthenia Gravis clinical trial biotechnology antibody therapeutics
Sentiment note

The company is presenting clinical trial results, which indicates ongoing research and development without clear positive or negative outcome indicators

Positive GlobeNewswire Inc. • N/A
Dianthus Therapeutics Completes Enrollment of Phase 2 MaGic Trial of DNTH103 in Generalized Myasthenia Gravis With Top-Line Results Expected in September

Dianthus Therapeutics has completed enrollment in the Phase 2 MaGic trial of its investigational drug DNTH103 for generalized Myasthenia Gravis. Top-line results are expected in September 2025. DNTH103 is also being evaluated in trials for Chronic Inflammatory Demyelinating Polyneuropathy and Multifocal Motor Neuropathy.

DNTH Dianthus Therapeutics DNTH103 Generalized Myasthenia Gravis Phase 2 trial Chronic Inflammatory Demyelinating Polyneuropathy Multifocal Motor Neuropathy
Sentiment note

The article highlights Dianthus Therapeutics' progress in advancing its investigational drug DNTH103 through clinical trials for multiple autoimmune disorders, indicating the company's strong pipeline and development capabilities.

News and sentiment labels describe article tone and are provided for research purposes only. They are not trading recommendations or forecasts.
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