CYTK
Cytokinetics, Incorporated · Healthcare · Biotechnology
Last
$64.55
+$1.12 (+1.76%) 9:58 AM ET
Prev close $63.43
Open $63.27
Day high $65.07
Day low $63.27
Volume 86,189
Avg vol 2,102,787
Mkt cap
$8.82B
EV/Sales
143.49
P/E ratio
-10.04
FY Revenue
$67.67M
EPS
-6.43
Gross Margin
92.19%
Div yield
0.00%
Sector
Healthcare
AI report sections
CYTK
Cytokinetics, Incorporated
Cytokinetics exhibits strong long-term price appreciation, with the stock up roughly 76% over the past year and trading near the upper end of its 52-week range, supported by price levels above short- and medium-term moving averages. At the same time, fundamentals show deep losses, negative free cash flow, and a highly leveraged balance sheet, with negative equity and large operating cash burn. Valuation multiples such as P/S and EV/Sales appear elevated relative to current revenue and profitability, while short interest is sizable, indicating non-trivial sentiment and squeeze risk.
AI summarized at 12:28 AM ET, 2026-04-01
AI summary scores
INTRADAY: 63 SWING: 66 LONG: 34
Volume vs average
Intraday (cumulative)
−15% (Below avg)
Vol/Avg: 0.85×
RSI
38.77 (Weak)
Weak (30–40)
MACD momentum
Intraday
-0.03 (Weak)
MACD: 0.02 Signal: 0.06
Short-Term
+0.16 (Strong)
MACD: -2.62 Signal: -2.78
Long-Term
-0.10 (Weak)
MACD: -4.69 Signal: -4.59
Intraday trend score 51.34

Latest news

CYTK 12 articles Positive: 8 Neutral: 4 Negative: 0
Positive GlobeNewswire Inc. • Na
Cytokinetics Announces Four Upcoming Presentations at the HFSA Annual Scientific Meeting 2026

Cytokinetics announced four presentations at the Heart Failure Society of America Annual Scientific Meeting in October 2026, including two late-breaking clinical research presentations on aficamten (MYQORZO) for hypertrophic cardiomyopathy. The company plans to submit a Supplemental New Drug Application for aficamten in non-obstructive HCM in Q4 2026 following positive Phase 3 trial results.

CYTK aficamten MYQORZO hypertrophic cardiomyopathy HCM clinical trial ACACIA-HCM SEQUOIA-HCM
Sentiment note

The company is presenting positive clinical trial results for aficamten at a major medical conference and plans to submit a regulatory application for label expansion in non-obstructive HCM. Multiple late-breaking presentations and oral presentations demonstrate progress in clinical development and potential market expansion for an already-approved drug.

Neutral The Motley Fool • Sara Appino
AbbVie vs. Bristol Myers Squibb: Which Healthcare Stock Is a Better Buy in 2026?

AbbVie and Bristol Myers Squibb are compared as pharmaceutical investment options for 2026. AbbVie is recommended as the better buy due to its successful immunology franchise with Skyrizi and Rinvoq driving growth, diversification into aesthetics and neuroscience, and having navigated its patent cliff challenges. Bristol Myers Squibb, while cheaper on valuation metrics and maintaining strong profit margins, faces revenue stagnation, legal uncertainties from a Celgene acquisition lawsuit, and is still working through its own portfolio transition challenges.

ABBV BMY CELGR MCK pharmaceutical stocks immunology oncology patent cliff
Sentiment note

Mentioned as involved in patent disputes with Bristol Myers Squibb; no specific sentiment expressed beyond noting the legal conflict.

Positive Zacks Investment Research • Na
Will Camzyos' Long-Term Benefits Strengthen BMY's Growth Outlook?

Bristol Myers Squibb's Camzyos demonstrated durable reductions in LVOT obstruction over five years with 97.4% of patients achieving target gradients. Sales surged 74% year-over-year to $729 million in H1 2026. The company seeks FDA approval for adolescents with a decision expected by September 30, 2026. However, competition is intensifying with Cytokinetics' Myqorzo approved in December 2025 and Edgewise Therapeutics advancing EDG-7500 in clinical trials.

BMY CELGR CYTK EWTX Camzyos mavacamten obstructive hypertrophic cardiomyopathy cardiac myosin inhibitor
Sentiment note

Myqorzo received FDA approval in December 2025 as first approved product, showing encouraging initial uptake and representing successful transition to commercial-stage company. Plans to expand label to non-obstructive HCM in Q4 2026.

Positive GlobeNewswire Inc. • Na
Cytokinetics to Participate in September Investor Conferences

Cytokinetics announced that management will participate in multiple investor conferences in September 2026. The company highlighted positive results from its ACACIA-HCM Phase 3 clinical trial for aficamten in non-obstructive hypertrophic cardiomyopathy (nHCM), with plans to submit a Supplemental New Drug Application in Q4 2026. The trial demonstrated statistically significant improvements in both patient-reported and physician-assessed endpoints.

CYTK Cytokinetics aficamten MYQORZO ACACIA-HCM hypertrophic cardiomyopathy Phase 3 trial cardiac myosin inhibitor
Sentiment note

The company announced positive Phase 3 clinical trial results for aficamten in nHCM with statistically significant improvements across both patient-reported and physician-assessed endpoints. Plans to submit a Supplemental New Drug Application in Q4 2026 indicate regulatory progress. Active participation in major investor conferences demonstrates confidence and investor engagement.

Positive Zacks Investment Research • Na
Can CYTK's Aficamten Strengthen Its HCM Growth Prospects?

Cytokinetics announced additional positive results from ACACIA-HCM and MAPLE-HCM studies showing aficamten improved cardiac structure and diastolic function in non-obstructive HCM patients, and outperformed metoprolol in obstructive HCM. The company plans to file for nHCM approval in Q4 2026, potentially expanding the drug's addressable market. Myqorzo received FDA approval in December 2025 for obstructive HCM treatment.

CYTK BMY CELGR EWTX aficamten Myqorzo hypertrophic cardiomyopathy HCM
Sentiment note

Company demonstrated positive clinical trial results with aficamten showing efficacy in both obstructive and non-obstructive HCM, received FDA approval for Myqorzo in December 2025, and has plans for label expansion with nHCM filing in Q4 2026, positioning the drug as a meaningful commercial opportunity.

Positive GlobeNewswire Inc. • Cytokinetics, Incorporated
Cytokinetics Announces Additional Results from ACACIA-HCM and MAPLE-HCM Presented in Late Breaking Clinical Trial Session at the European Society of Cardiology (ESC) Congress 2026

Cytokinetics presented additional clinical trial results for aficamten (MYQORZO) at the ESC Congress 2026. ACACIA-HCM data showed aficamten improved cardiac structure and diastolic function in non-obstructive HCM patients beyond exercise capacity improvements. MAPLE-HCM analysis demonstrated aficamten outperformed metoprolol across different pre-trial treatment groups in obstructive HCM patients. The company plans to submit a Supplemental New Drug Application for non-obstructive HCM in Q4 2026.

CYTK aficamten MYQORZO hypertrophic cardiomyopathy HCM cardiac myosin inhibitor ACACIA-HCM MAPLE-HCM
Sentiment note

Company announced positive additional clinical trial results for aficamten showing improvements in cardiac structure and diastolic function in non-obstructive HCM patients, and demonstrated superiority over metoprolol in obstructive HCM patients. Results support potential regulatory approval and market expansion, with plans to submit supplemental application in Q4 2026. Data published in major medical journals strengthens clinical evidence.

Positive The Motley Fool • Jack Delaney
Insider Transaction: Cytokinetics CEO Robert Blum Sells 7,500 Shares for $575,700

Cytokinetics CEO Robert Blum exercised 7,500 stock options at a strike price of $10.60 and sold them at a weighted-average price of $76.76, generating $575,700. Despite the sale, Blum retains substantial equity holdings of 377,820 direct shares and 4,166 indirect shares, indicating continued alignment with shareholders. Analysts view the transaction as routine profit-taking given the stock's 100% gain over the past 12 months, with 91% of analysts rating the stock a buy and a median price target of $107.50.

CYTK insider transaction stock options exercise CEO stock sale cardiac therapeutics biopharmaceutical MYQORZO equity holdings
Sentiment note

The CEO's sale is characterized as routine profit-taking rather than a bearish signal. The company has strong analyst support (91% buy ratings), a median price target of $107.50 (40% upside), and the stock has outperformed the S&P 500 significantly with 100% gains over 12 months. The CEO maintains substantial equity holdings, demonstrating continued confidence in the company's direction.

Positive GlobeNewswire Inc. • Na
Cytokinetics to Announce Second Quarter Results on August 6, 2026

Cytokinetics announced it will report second quarter 2026 results on August 6, 2026, followed by a conference call at 4:30 PM ET. The company highlighted positive topline results from its ACACIA-HCM Phase 3 trial of aficamten in non-obstructive hypertrophic cardiomyopathy patients and plans to discuss findings with regulatory authorities.

CYTK earnings report Q2 2026 aficamten MYQORZO ACACIA-HCM hypertrophic cardiomyopathy cardiac myosin inhibitor
Sentiment note

The company reported positive topline results from its Phase 3 ACACIA-HCM trial for aficamten in non-obstructive HCM patients, indicating progress in pipeline development. The company has an approved product (MYQORZO) in multiple markets and is advancing multiple investigational candidates, demonstrating strong clinical momentum and regulatory progress.

Positive The Motley Fool • Jonathan Ponciano
What This Cytokinetics Insider Sale Might Mean With the Stock Up 110%

Cytokinetics CEO Robert Blum sold 7,500 shares at $82.02 per share after exercising options at $10.60, generating $615,150 in proceeds. The sale represents only 2% of his total equity holdings, with the CEO retaining 381,986 shares and 186,745 options. The transaction appears to be routine diversification following the company's successful MYQORZO drug launch, which generated $4.8 million in first-quarter revenue and has been prescribed to approximately 680 patients by over 275 doctors.

CYTK insider sale stock options CEO diversification MYQORZO launch biopharmaceutical cardiac myosin inhibitor hypertrophic cardiomyopathy
Sentiment note

The insider sale is characterized as routine diversification rather than a bearish signal. The CEO retains substantial holdings (381,986 shares plus 186,745 options), indicating confidence in the company. The stock has surged 110% over the past year, and MYQORZO's successful market launch with strong early adoption metrics (680 patients, 275+ prescribing doctors) and international expansion to Germany support positive momentum.

Neutral GlobeNewswire Inc. • Na
Cytokinetics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

Cytokinetics granted stock options, restricted stock units (RSUs), and performance stock units (PSUs) to 12 newly hired employees as material inducements to employment. The grants include 24,784 stock options at $71.38 per share, 16,429 RSUs vesting over 3 years, and 2,242 PSUs tied to performance goals. The awards were granted in accordance with Nasdaq Listing Rule 5635(c)(4).

CYTK stock options RSUs PSUs employee compensation equity incentives vesting schedule Nasdaq Listing Rule 5635
Sentiment note

The article announces routine employee equity grants as hiring incentives. While this indicates business growth and hiring activity, it is a standard corporate practice with no material impact on company operations, financial performance, or product development. The announcement is informational rather than indicative of positive or negative business developments.

Neutral GlobeNewswire Inc. • Na
Cytokinetics to Participate in June Investor Conferences

Cytokinetics announced that its management team will participate in two major investor conferences in June 2026: the Jefferies Global Healthcare Conference on June 3 and the Goldman Sachs 47th Annual Global Healthcare Conference on June 8. The company will host fireside chats at both events, with live webcasts available on its investor relations website.

CYTK investor conference Jefferies Global Healthcare Conference Goldman Sachs Healthcare Conference cardiac myosin inhibitor MYQORZO aficamten hypertrophic cardiomyopathy
Sentiment note

The announcement is routine corporate communication regarding investor conference participation. While the company has an approved drug (MYQORZO) and positive Phase 3 trial results (ACACIA-HCM), the article itself is purely informational about conference attendance without new clinical or financial developments that would warrant positive or negative sentiment.

Neutral GlobeNewswire Inc. • Na
Cytokinetics Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)

Cytokinetics granted stock options to purchase 20,807 shares and 13,793 RSUs to 8 newly hired employees on May 15, 2026 as material inducements to employment. The stock options have an exercise price of $75.85 per share and vest over 4 years, while RSUs vest over 3 years. The company is a specialty cardiovascular biopharmaceutical firm with its approved drug MYQORZO® for obstructive hypertrophic cardiomyopathy and several investigational candidates in development.

CYTK stock options RSUs employee compensation equity incentive plan cardiac myosin inhibitor MYQORZO® hypertrophic cardiomyopathy
Sentiment note

The article reports a routine employee equity grant as a hiring incentive, which is standard corporate practice. While the company has an approved drug (MYQORZO®) and positive clinical trial results (ACACIA-HCM), the main article focuses on administrative compensation matters rather than business developments or financial performance that would warrant positive or negative sentiment.

News and sentiment labels describe article tone and are provided for research purposes only. They are not trading recommendations or forecasts.
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