CTMX
CytomX Therapeutics, Inc. · Healthcare · Biotechnology
Last
$5.36
−$0.13 (−2.28%) 4:00 PM ET
After hours $5.35 −$0.01 (−0.12%) 7:03 AM ET
Prev close $5.48
Open $5.30
Day high $5.44
Day low $5.29
Volume 2,558,802
Avg vol 3,582,933
Mkt cap
$909.87M
P/E ratio
13.06
FY Revenue
$113.63M
EPS
0.41
Gross Margin
100.00%
Sector
Healthcare
AI report sections
CTMX
CytomX Therapeutics, Inc.
CytomX Therapeutics, Inc. exhibits strong recent price momentum with the latest close near its 52-week high and well above key moving averages. At the same time, overbought technical readings, negative revenue and earnings growth, and deeply negative free cash flow highlight elevated risk and fundamental pressure. Valuation multiples appear demanding relative to shrinking earnings and cash burn, while meaningful short interest suggests ongoing skepticism despite constructive news flow.
AI summarized at 8:37 PM ET, 2026-01-16
AI summary scores
INTRADAY: 63 SWING: 72 LONG: 47
Volume vs average
Intraday (cumulative)
−8% (Below avg)
Vol/Avg: 0.92×
RSI
52.16 (Neutral)
Neutral (40–60)
MACD momentum
Intraday
+0.00 (Strong)
MACD: 0.01 Signal: 0.00
Short-Term
-0.04 (Weak)
MACD: 0.12 Signal: 0.16
Long-Term
-0.03 (Weak)
MACD: 0.34 Signal: 0.37
Intraday trend score 38.60

Latest news

CTMX 12 articles Positive: 4 Neutral: 4 Negative: 0
Neutral GlobeNewswire Inc. • Not Specified
CytomX Therapeutics to Present at Upcoming February Conferences

CytomX Therapeutics announced that management will participate in two upcoming conferences in February 2026: the Guggenheim Emerging Outlook Biotech Summit on February 11 in New York and World ADC London on February 25 in London. The clinical-stage biopharmaceutical company, focused on conditionally activated biologics for oncology, continues to advance its pipeline including varsetatug masetecan and CX-801.

CTMX AMGN BMY CELGR CytomX Therapeutics masked biologics PROBODY platform varsetatug masetecan
Sentiment note

The announcement is routine corporate disclosure regarding conference participation. While it demonstrates continued investor engagement and pipeline advancement, there is no material clinical data, financial results, or strategic developments that would warrant positive or negative sentiment. The tone is informational rather than indicative of significant company progress or setbacks.

Positive GlobeNewswire Inc. • Cytomx Therapeutics
CytomX Therapeutics to Present at the Jefferies London Healthcare Conference

CytomX Therapeutics, a clinical-stage oncology-focused biopharmaceutical company, announced upcoming presentations of its clinical-stage pipeline including CX-2051 and CX-801, with Phase 1 data updates expected in early 2026.

CTMX AMGN ALPMY BMY oncology biologics cancer treatment clinical trials
Sentiment note

Company is progressing clinical trials, presenting new data, and has strategic collaborations with major pharmaceutical companies

Neutral GlobeNewswire Inc. • Cytomx Therapeutics
CytomX Therapeutics to Report Third Quarter 2025 Financial Results on November 6, 2025

CytomX Therapeutics will report its third quarter financial results on November 6, 2025, after market close, followed by a conference call and webcast at 5:00 p.m. ET.

CTMX AMGN ALPMY BMY financial results conference call webcast oncology
Sentiment note

Standard financial reporting announcement with no explicit positive or negative indicators

Positive Benzinga • Benzinga Staff Writer
12 Health Care Stocks Moving In Thursday's After-Market Session

Multiple healthcare stocks experienced significant price movements during Thursday's after-market trading session, with some companies seeing notable gains while others experienced declines.

CTMX GLTO DRIO ORGO healthcare stocks after-market trading
Sentiment note

Stock increased by 9.14% to $3.1, with a market value of $397.4 million

Neutral The Motley Fool • Na
CytomX (CTMX) Q2 Revenue Drops 26%

CytomX Therapeutics reported Q2 2025 results with declining revenue, reduced operating expenses, and positive clinical pipeline progress, particularly for its lead colorectal cancer candidate CX-2051.

CTMX BMY CELGR AMGN biotechnology oncology clinical trials revenue decline
Sentiment note

Mixed financial performance with revenue decline (-25.6%) offset by cost controls, positive clinical pipeline developments, and a $100 million capital raise ensuring cash runway through Q2 2027

Neutral Benzinga • Prnewswire
Breaking Through: Systemic Genetic Medicines for Hard-to-Treat Cancers

Calidi Biotherapeutics is developing a groundbreaking genetic medicine platform using engineered viruses to precisely target and treat metastatic cancers, with promising preclinical data presented at AACR and ASCO conferences.

CLDI VRTX IBRX CRSP cancer genetic medicine virotherapy oncology
Sentiment note

Updated pipeline priorities focusing on developing CX-2051 for metastatic colorectal cancer

Positive GlobeNewswire Inc. • Cytomx Therapeutics
CytomX Therapeutics Presents Preclinical Data for mRNA Encoded Masked IL-12 Molecule in Collaboration with Moderna at AACR Annual Meeting

CytomX Therapeutics and Moderna presented preclinical data on an mRNA-encoded masked IL-12 molecule, which showed potent anti-tumor activity with enhanced tolerability.

CTMX MRNA CytomX Therapeutics Moderna mRNA IL-12 cancer preclinical
Sentiment note

The article highlights the positive preclinical data for CytomX's mRNA-encoded masked IL-12 molecule, which demonstrated improved anti-tumor efficacy and tolerability.

Positive GlobeNewswire Inc. • N/A
CytomX Therapeutics to Present at the Barclays 27th Annual Global Healthcare Conference

CytomX Therapeutics, a biopharmaceutical company focused on developing novel conditionally activated biologics for cancer treatment, announced that its CEO will present at the Barclays Global Healthcare Conference. The company's pipeline includes several clinical-stage candidates targeting various cancer types.

CTMX CytomX Therapeutics cancer treatment biologics Barclays Global Healthcare Conference
Sentiment note

The article highlights CytomX's progress in developing a pipeline of novel cancer treatments, which suggests the company is making advancements in its field.

Unknown GlobeNewswire Inc. • CytomX Therapeutics Inc.
CytomX Therapeutics Promotes Chris Ogden to Chief Financial Officer

SOUTH SAN FRANCISCO, Calif., June 17, 2024 (GLOBE NEWSWIRE) -- CytomX Therapeutics, Inc. (Nasdaq: CTMX), a leader in the field of masked, conditionally activated biologics, today announced the promotion of Chris Ogden to Chief Financial Officer effective June 15, 2024.

CTMX Directors and Officers Health
Unknown GlobeNewswire Inc. • CytomX Therapeutics Inc.
CytomX Therapeutics to Present at the Jefferies Global Healthcare Conference

SOUTH SAN FRANCISCO, Calif., May 22, 2024 (GLOBE NEWSWIRE) -- CytomX Therapeutics, Inc. (Nasdaq: CTMX), a leader in the field of masked, conditionally activated biologic therapeutics, today announced that Sean McCarthy, D.Phil., chief executive officer and chairman, will present at the Jefferies Global Healthcare Conference on Thursday, June 6, 2024, at 8:30 a.m. ET.

CTMX Calendar of Events
Unknown GlobeNewswire Inc. • CytomX Therapeutics Inc.
CytomX Therapeutics Announces New Employment Inducement Grants

SOUTH SAN FRANCISCO, Calif., May 16, 2024 (GLOBE NEWSWIRE) -- CytomX Therapeutics, Inc. (Nasdaq: CTMX), a leader in the field of masked, conditionally activated biologics, today announced that on May 15, 2024, the Company granted two new employees options to purchase a total of 130,000 shares of the Company’s common stock at an exercise price per share equal to $1.96, which was the closing price on May 15, 2024, the date of the grants.

CTMX Health Major shareholder announcements
Unknown Benzinga • Vandana Singh
Analysts' Varied Perspectives On CytomX's CX-904 Cancer Study: Safety Profile But Caution in Pancreatic Cancer

Wednesday, CytomX Therapeutics Inc (NASDAQ:CTMX) released initial data from the ongoing CX-904 Phase 1a dose escalation clinical study, demonstrating a favorable safety profile and confirmed anti-cancer activity.  As of April 16, 2024, data cutoff, the Phase 1 study enrolled 35 heavily pretreated patients with advanced metastatic solid tumor types. CX-904 demonstrated a favorable safety profile, supporting administration and monitoring enrolled patients in an outpatient setting. Eight patients had measurable tumor reduction at data cutoff, including 2 of 6 efficacy-evaluable patients (33%) with pancreatic cancer with confirmed partial responses. All six efficacy-evaluable patients with pancreatic cancer achieved disease control (objective response or stable disease).  One patient (6 mg target dose) achieved an 83% tumor reduction for the two patients with a confirmed partial response. The second patient (5 mg target dose) with a confirmed response achieved a 51% ...Full story available on Benzinga.com

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News and sentiment labels describe article tone and are provided for research purposes only. They are not trading recommendations or forecasts.
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