CRL
Charles River Laboratories International, Inc. · Healthcare · Diagnostics & Research
Last
$301.94
+$2.92 (+0.98%) 3:59 PM ET
Prev close $299.02
Open $294.95
Day high $310.08
Day low $294.95
Volume 805,566
Avg vol 967,612
Mkt cap
$14.42B
EV/Sales
4.21
P/E ratio
-60.39
FY Revenue
$4.00B
EPS
-5.00
Gross Margin
32.67%
Div yield
0.00%
Sector
Healthcare
AI report sections
CRL
Charles River Laboratories International, Inc.
No AI report section text found yet for this symbol.
AI summarized at 10:26 AM ET, 2026-10-05
AI summary scores
INTRADAY: 81 SWING: 84 LONG: 37
Volume vs average
Intraday (cumulative)
+22% (Above avg)
Vol/Avg: 1.22×
RSI
56.49 (Neutral)
Neutral (40–60)
MACD momentum
Intraday
-0.26 (Weak)
MACD: -0.14 Signal: 0.12
Short-Term
+0.18 (Strong)
MACD: 5.97 Signal: 5.79
Long-Term
+0.02 (Strong)
MACD: 13.20 Signal: 13.17
Intraday trend score 47.58

Latest news

CRL 12 articles Positive: 8 Neutral: 3 Negative: 1
Positive GlobeNewswire Inc. • Researchandmarkets.Com
Global Synthetic Antibody Library Market Report 2026: Size and Forecast to 2030 | Capitalize on 12% CAGR and AI Design with Charles River, Twist Bioscience, GenScript and AbCellera

The global synthetic antibody library market is projected to grow from $1.63 billion in 2025 to $2.86 billion by 2030, representing a 12% CAGR. Growth is driven by AI-integrated antibody design, increased demand for therapeutic antibodies, high-throughput screening technologies, and expansion of contract research organizations. North America leads the market while Asia-Pacific shows fastest growth potential.

CRL TWST ABCL synthetic antibody library AI-driven drug discovery therapeutic antibodies phage display yeast display
Sentiment note

Featured as a prominent player in the synthetic antibody library market during a period of strong market expansion (12% CAGR through 2030), indicating strong positioning in a growing sector.

Negative Zacks Investment Research • Na
PGNY or CRL: Which Is the Better Value Stock Right Now?

A comparison of two Medical Services stocks reveals that Progyny (PGNY) presents a more attractive value investment opportunity than Charles River Laboratories (CRL). PGNY has a Zacks Rank of #2 (Buy) versus CRL's #3 (Hold), along with superior valuation metrics including a lower forward P/E ratio (12.40 vs 26.89) and a better Value grade (B vs D).

PGNY CRL value investing valuation metrics P/E ratio PEG ratio Zacks Rank Medical Services stocks
Sentiment note

CRL shows weaker value metrics with a Zacks Rank #3 (Hold), higher forward P/E ratio of 26.89, PEG ratio of 2.86, and a Value grade of D, indicating it is less attractive as a value investment compared to PGNY.

Neutral Zacks Investment Research • Na
Charles River Gains 75.8% in a Year: What's Driving the Rally?

Charles River Laboratories (CRL) has outperformed the market with a 75.8% share price increase over the past year, driven by strong Research Models and Services (RMS) prospects and adoption of new approach methodologies. However, the company faces headwinds from uneven demand recovery across client segments, with small and midsized biotech revenues flat and currency fluctuations impacting reported growth. The company maintains a Zacks Rank #3 (Hold) rating.

CRL VCYT GMED TFX contract research organization drug development biotech funding research models
Sentiment note

Strong share price momentum (75.8% gain) and positive developments in RMS and new methodologies are offset by uneven demand recovery, flat small biotech revenues, and currency headwinds. Hold rating reflects balanced risk-reward profile.

Positive GlobeNewswire Inc. • Researchandmarkets.Com
Global Animal Model Market Report 2026-2034 by Animal Type, Technology, Application, End User, and Region | CRISPR and Drug Discovery Drive Growth to USD 3.31 Billion

The global animal model market is projected to grow from USD 2.02 billion in 2025 to USD 3.31 billion by 2034, expanding at a CAGR of 5.46%. Growth is driven by rising pharmaceutical research, CRISPR-Cas9 advances, personalized medicine demand, and vaccine R&D expansion. Rodents remain the dominant animal type, while key players include Charles River Laboratories, Eurofins Scientific, and The Jackson Laboratory.

CRL ERRFY animal model market CRISPR-Cas9 drug discovery personalized medicine pharmaceutical research genetic disease research
Sentiment note

Listed as a key market participant in the growing animal model market, which is projected to expand at 5.46% CAGR through 2034, driven by increased pharmaceutical research and CRISPR adoption.

Positive Zacks Investment Research • Na
Is It Prudent to Add Teleflex Stock to Your Portfolio Now?

Teleflex (TFX) reported Q2 2026 Vascular revenue growth of 9% driven by central access and hemostatic product demand, with Asia revenues jumping 59.5%. However, tariffs and acquisition costs pressured margins, with adjusted operating margin declining 520 basis points. The company improved its balance sheet with pro forma net leverage at 1.9X after debt repayment.

TFX VCYT GMED CRL Teleflex Vascular business Q2 2026 earnings Asia expansion
Sentiment note

Consistent earnings beats in trailing four quarters (average surprise 5.9%), positive stock performance of 4% over the past year, and Zacks Rank #1 rating. Long-term earnings growth rate of 9.4% provides solid growth outlook.

Positive GlobeNewswire Inc. • Researchandmarkets.Com
Cell and Gene Therapy Biomanufacturing Market - Size, Share, and Forecast, 2026-2031 | Automation, Viral Vectors, and CDMO Expansion Drive 11.7% CAGR to $8.7 Billion

The global cell and gene therapy biomanufacturing market is projected to grow from $5.0 billion in 2026 to $8.7 billion by 2031, driven by an 11.7% CAGR. Growth is fueled by increasing regulatory approvals, rising demand for scalable manufacturing infrastructure, and investments in automation and modular systems. However, high production costs, regulatory complexity, and workforce shortages remain significant challenges.

LZAGY TMO MKKGY DHR cell and gene therapy biomanufacturing viral vectors CDMO
Sentiment note

Listed among key players, positioned to benefit from increased demand for quality testing, bioprocessing services, and manufacturing support in the growing market.

Positive Zacks Investment Research • Zacks.Com
Is Aveanna Healthcare (AVAH) Stock Outpacing Its Medical Peers This Year?

Aveanna Healthcare (AVAH) has significantly outperformed the Medical sector year-to-date, returning 56.4% compared to the sector's 2.8% average return. The company holds a Zacks Rank #2 (Buy) with consensus earnings estimates up 23.2% in the past quarter, indicating improved analyst sentiment. Charles River Laboratories (CRL) is another Medical stock outperforming with a 48.4% year-to-date return.

AVAH CRL Aveanna Healthcare Medical sector stock performance earnings estimates Zacks Rank outpatient healthcare
Sentiment note

Solid year-to-date performance of 48.4% outperforming its Medical Services industry. Holds Zacks Rank #2 (Buy) rating with a 3.3% increase in consensus EPS estimates over the past three months, indicating positive momentum.

Positive GlobeNewswire Inc. • Researchandmarkets.Com
Pharmaceutical Impurity Synthesis and Isolation Services Report: Capitalize on a $2.1 Billion Market by 2030 as Tariffs and 8.9% Isolation Growth Reshape Competition Across Eurofins, WuXi AppTec, Cambrex and Charles River

The global pharmaceutical impurity synthesis and isolation services market is projected to grow from $1.3 billion in 2024 to $2.1 billion by 2030 at a 7.7% CAGR. Growth is driven by stricter regulatory requirements, increasing drug complexity, biologics expansion, and rising pharmaceutical outsourcing. Isolation services are expected to grow fastest at 8.9% CAGR, while analytical services will advance at 5.7% CAGR.

CRL ERRFY WUXAY pharmaceutical impurity services isolation services analytical services drug development regulatory compliance
Sentiment note

Named among leading companies in a growing market driven by stricter regulatory requirements, drug complexity, and outsourcing trends favoring specialized service providers.

Positive GlobeNewswire Inc. • Researchandmarkets.Com
Rare Disease Contract Research Organization (CRO) Market Outlook 2026-2030: Investment Trends, Strategic Profiles and Revenue Share Outlook

The global rare disease CRO market is projected to grow from $2.07 billion in 2025 to $3.16 billion by 2030, with an 8.9% CAGR. Growth is driven by expanding gene and cell therapy pipelines, increasing orphan drug approvals, precision medicine adoption, and decentralized clinical trials. Key trends include AI integration, patient registries, and real-world evidence utilization.

TMO IQV LH ICLR rare disease CRO gene therapy cell therapy orphan drugs
Sentiment note

Featured as a major player in the rare disease CRO market, benefiting from rising R&D spending and demand for specialized clinical trial management services.

Neutral Zacks Investment Research • Na
PGNY vs. CRL: Which Stock Is the Better Value Option?

A comparison of two Medical Services sector stocks, Progyny (PGNY) and Charles River Laboratories (CRL), both with Zacks Rank #2 (Buy). Based on valuation metrics including forward P/E ratio (12.92 vs 24.87), PEG ratio (1.12 vs 2.76), and Value grades (B vs D), Progyny is identified as the superior value opportunity.

PGNY CRL valuation Medical Services P/E ratio PEG ratio value investing Zacks Rank
Sentiment note

While maintaining Zacks Rank #2 (Buy) with positive earnings outlook, higher forward P/E (24.87), higher PEG ratio (2.76), and weaker Value grade (D) suggest less attractive valuation relative to Progyny.

Positive Zacks Investment Research • Na
Beat the Market the Zacks Way: FIGS, Microsoft, Amphenol in Focus

Zacks Investment Research showcases the performance of its various stock rating systems and portfolios. The Zacks Rank #1 portfolio outperformed the S&P 500 by 2.3 percentage points year-to-date, while individual stocks like FIGS and CRL surged following rank upgrades. The Focus List, ECAP, ECDP, and Top 10 portfolios also demonstrated strong returns, with the Top 10 portfolio delivering a cumulative return of +2,881.3% since 2012 compared to the S&P 500's +648.5%.

FIGS CRL APH CIB stock ratings portfolio performance Zacks Rank market outperformance
Sentiment note

Stock returned 21.1% following upgrade to Zacks Rank #2 on July 14

Neutral Zacks Investment Research • Zacks.Com
Charles River (CRL) Up 10.5% Since Last Earnings Report: Can It Continue?

Charles River Laboratories (CRL) shares have gained 10.5% since its Q2 2026 earnings report, outperforming the S&P 500. The company beat earnings estimates with non-GAAP EPS of $3.02 and raised its 2026 guidance, though revenues declined 2.7% year-over-year. However, estimates have been trending downward since the earnings release, and the stock carries weak VGM scores despite maintaining a Zacks Rank #2 (Buy) rating.

CRL HCA earnings report revenue decline guidance raised estimate revisions stock performance operating margins
Sentiment note

Mixed signals: positive near-term stock performance (+10.5%) and raised 2026 guidance, but offset by declining revenues (-2.7%), downward estimate revisions post-earnings, weak Growth (D) and Momentum (F) scores, and overall VGM Score of F. The Zacks Rank #2 (Buy) suggests potential, but fundamental weakness and negative estimate trends indicate caution.

News and sentiment labels describe article tone and are provided for research purposes only. They are not trading recommendations or forecasts.
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