CMPX
Compass Therapeutics, Inc. · Healthcare · Biotechnology
At close
$2.08
$0.00 (0.00%) Close
Pre-market $2.09 +$0.01 (+0.48%) 1:18 AM ET
Prev close $2.08
Open $2.07
Day high $2.08
Day low $2.07
Volume 20,133
Avg vol 12,936,199
Mkt cap
$374.58M
P/E ratio
-5.20
EPS
-0.40
Sector
Healthcare
AI report sections
CMPX
Compass Therapeutics, Inc.
Compass Therapeutics shows a pronounced upward price trend over the past year, with the latest close near the top of its 52-week range and above key moving averages. At the same time, the company remains loss-making with negative operating cash flow and relies on external financing, which introduces fundamental risk despite a sizable cash position. Short interest and short volume are elevated, indicating a meaningful level of skepticism or hedging against the recent strength.
AI summarized at 12:18 PM ET, 2026-01-14
AI summary scores
INTRADAY: 72 SWING: 78 LONG: 46
Volume vs average
Intraday (cumulative)
+8% (Above avg)
Vol/Avg: 1.08×
RSI
40.23 (Neutral)
Neutral (40–60)
MACD momentum
Intraday
-0.00 (Weak)
MACD: -0.00 Signal: -0.00
Short-Term
+0.18 (Strong)
MACD: -0.35 Signal: -0.53
Long-Term
+0.11 (Strong)
MACD: -0.92 Signal: -1.03
Intraday trend score 54.16

Latest news

CMPX 12 articles Positive: 6 Neutral: 4 Negative: 1
Positive GlobeNewswire Inc. • Na
Compass Therapeutics to Present Promising Phase 1 Clinical Data for CTX-8371 in Patients with Advanced Malignancies Treated in the Post-Checkpoint Inhibitor Setting at the 2026 ASCO Annual Meeting

Compass Therapeutics announced Phase 1 clinical data for CTX-8371, a novel PD-1×PD-L1 bispecific antibody, showing promising monotherapy activity in patients with advanced malignancies resistant to prior checkpoint inhibitors. The drug demonstrated deep and durable responses in triple-negative breast cancer, Hodgkin lymphoma, and non-small cell lung cancer, with a 33% overall response rate at the highest dose levels and no dose-limiting toxicities observed.

CMPX CTX-8371 PD-1×PD-L1 bispecific antibody Phase 1 clinical trial checkpoint inhibitor triple-negative breast cancer Hodgkin lymphoma non-small cell lung cancer
Sentiment note

The company reported promising Phase 1 clinical data for CTX-8371 with deep and durable responses in multiple cancer types, a favorable safety profile with no dose-limiting toxicities, and plans to expand cohorts and report additional data in Q4 2026. These positive clinical results support advancement of the therapeutic candidate.

Negative GlobeNewswire Inc. • Johnson Fistel, Pllp
Compass Therapeutics, Inc. Shareholders Are Encouraged to Reach Out to Johnson Fistel for More Information About Potentially Recovering Their Losses

Johnson Fistel, PLLP is investigating potential securities law violations by Compass Therapeutics following the disclosure that its lead drug candidate tovecimig failed to meet the overall survival secondary endpoint in the COMPANION-002 clinical trial. The company reported median overall survival of 8.9 months versus 9.4 months for the control arm, resulting in significant stock price decline. Investors who suffered losses are encouraged to contact the firm.

CMPX securities fraud investigation clinical trial failure overall survival endpoint investor losses federal securities laws stock price decline
Sentiment note

The company's lead drug candidate failed to meet its primary efficacy endpoint in clinical trials, with the treatment arm performing worse than the control arm. This failure triggered significant stock price decline and prompted a securities investigation, indicating serious concerns about the company's prospects and potential investor harm.

Neutral GlobeNewswire Inc. • Na
Compass Therapeutics to Announce Topline Secondary Endpoints from the Phase 2/3 COMPANION-002 Study of Tovecimig in Patients with Biliary Tract Cancer

Compass Therapeutics will host a webcast on April 27, 2026 to present topline secondary endpoints from its Phase 2/3 COMPANION-002 study evaluating tovecimig, a DLL4 x VEGF-A bispecific antibody combined with paclitaxel, in patients with advanced biliary tract cancer. The study has reached its prespecified event threshold of 80% overall survival events.

CMPX tovecimig biliary tract cancer Phase 2/3 clinical trial DLL4 x VEGF-A bispecific antibody oncology immunotherapy angiogenesis
Sentiment note

The announcement is procedural in nature, simply notifying investors of an upcoming webcast to discuss secondary endpoints. While reaching the prespecified event threshold is a positive milestone, the article does not disclose actual efficacy or safety data, making it impossible to assess whether the results are favorable or unfavorable. The neutral sentiment reflects the informational nature of the announcement without substantive clinical outcome details.

Positive GlobeNewswire Inc. • Compass Therapeutics
Compass Therapeutics to Participate in Upcoming December Investor Events

Compass Therapeutics announced participation in two healthcare investor conferences in December 2025, highlighting their ongoing clinical-stage oncology research focused on antibody-based therapeutics targeting tumor growth and immune system interactions.

CMPX oncology biopharmaceutical antibody therapeutics cancer research investor conferences
Sentiment note

Company is presenting at multiple investor conferences, showing ongoing research progress in developing novel cancer treatment antibodies with promising preclinical data on CTX-10726 demonstrating tumor elimination in studies

Positive GlobeNewswire Inc. • Compass Therapeutics
Compass Therapeutics to Participate in Upcoming September Investor Events

Compass Therapeutics will participate in multiple healthcare and investment conferences in September 2025, including events in Boston and New York, presenting their oncology-focused antibody-based therapeutics research.

CMPX CEP MS MSPA oncology biopharmaceutical conferences investment
Sentiment note

Company is actively engaging with investors, presenting at multiple prestigious conferences, indicating confidence in their clinical-stage research and potential growth

Neutral GlobeNewswire Inc. • Compass Therapeutics
Compass Therapeutics Announces Pricing of Upsized $120 Million Public Offering

Compass Therapeutics plans to raise approximately $120 million through a public offering of 33,290,000 common stock shares and pre-funded warrants at $3.00 per share, with the proceeds intended for research, clinical development, and corporate purposes.

CMPX JEF PIPR public offering stock fundraising oncology biopharmaceutical
Sentiment note

The company is conducting a standard public offering to raise capital for ongoing research and development, which is a typical financing strategy for clinical-stage biotech companies

Neutral Benzinga • Globe Newswire
Compass Therapeutics Announces Proposed Public Offering

Compass Therapeutics plans to launch an underwritten public offering of common stock and pre-funded warrants to fund research, clinical development, and commercial readiness preparations.

CMPX JEF PIPR public offering oncology biopharmaceutical antibody therapeutics
Sentiment note

The company is seeking funding for research and development, which is a standard practice for clinical-stage biotech companies. The offering indicates a need for capital but does not inherently suggest positive or negative performance.

Positive Investing.com • Marketbeat.Com
Top 3 High-Momentum Companies Analysts Are Still Bullish On

Three companies with recent stock rallies that analysts remain bullish on are Compass Therapeutics, Amprius Technologies, and Allot Communications. Analysts see significant upside potential in these momentum stocks despite their recent gains.

CMPX AMPX AMPX.WS ALLT momentum investing high-momentum stocks Compass Therapeutics Amprius Technologies
Sentiment note

Analysts have a consensus price target of $11.80, which is 266.5% above the current trading level, indicating significant upside potential despite the stock's recent 164% rally in the past year.

Positive GlobeNewswire Inc. • N/A
Compass Therapeutics to Participate in Upcoming Investor Events

Compass Therapeutics, a clinical-stage biopharmaceutical company, announced its participation in two investor conferences in September 2024, where it will present updates on its oncology-focused pipeline of antibody-based therapeutics.

CMPX Compass Therapeutics investor events oncology antibody-based therapeutics
Sentiment note

The article highlights Compass Therapeutics' participation in investor events, which suggests the company is actively engaging with the investment community and likely has positive developments to share about its pipeline and business.

Neutral GlobeNewswire Inc. • N/A
Eliem Therapeutics Announces Additions to its Leadership Team

Eliem Therapeutics announced the appointments of Brett Kaplan, M.D., as Chief Operating Officer, and Nishi Rampal, M.D., as Senior Vice President, Clinical Development. The new executives bring extensive experience in the pharmaceutical and biotechnology industries, which will help Eliem advance its pipeline of therapeutics for autoimmune-driven inflammatory diseases.

ELYM CMPX Eliem Therapeutics Brett Kaplan Nishi Rampal autoimmune diseases biotechnology
Sentiment note

The article states that Brett Kaplan previously served as a director of Compass Therapeutics, Inc., but does not provide any additional details about the company.

Positive GlobeNewswire Inc. • N/A
Compass Therapeutics to Participate in the Wedbush PacGrow Healthcare Conference

Compass Therapeutics, a clinical-stage biopharmaceutical company, announced that it will present at the Wedbush PacGrow Healthcare Conference on August 13, 2024. The company is developing proprietary antibody-based therapeutics to treat multiple human diseases, with a focus on the relationship between angiogenesis, the immune system, and tumor growth.

CMPX Compass Therapeutics Wedbush PacGrow Healthcare Conference oncology biopharmaceutical antibody-based therapeutics angiogenesis immune system
Sentiment note

The article presents Compass Therapeutics as a clinical-stage, oncology-focused biopharmaceutical company that is developing proprietary antibody-based therapeutics to treat multiple human diseases. The company's focus on the relationship between angiogenesis, the immune system, and tumor growth suggests a promising approach to cancer treatment, which is reflected in the positive sentiment.

Unknown GlobeNewswire Inc. • Compass Therapeutics
Compass Therapeutics to Participate in the Jefferies Global Healthcare Conference

BOSTON, May 30, 2024 (GLOBE NEWSWIRE) -- Compass Therapeutics, Inc. (Nasdaq: CMPX), a clinical-stage, oncology-focused biopharmaceutical company developing proprietary antibody-based therapeutics to treat multiple human diseases, today announced that the Company will participate in a fireside chat at the Jefferies Global Healthcare Conference taking place in New York City, NY June 5 – 6, 2024.

CMPX Calendar of Events Conference Calls/ Webcasts
News and sentiment labels describe article tone and are provided for research purposes only. They are not trading recommendations or forecasts.
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