CMPS
COMPASS Pathways plc · Healthcare · Medical Care Facilities
Last
$6.90
−$0.43 (−5.87%) 4:00 PM ET
After hours $6.96 +$0.06 (+0.87%) 4:27 AM ET
Prev close $7.33
Open $7.32
Day high $7.39
Day low $6.79
Volume 4,047,606
Avg vol 3,631,668
Mkt cap
$783.27M
P/E ratio
-2.54
EPS
-2.72
Sector
Healthcare
AI report sections
CMPS
COMPASS Pathways plc
CMPS exhibits strong upward price momentum over the past year with the stock trading near the top of its 52-week range, supported by bullish technical signals and elevated volume. At the same time, fundamentals remain weak with sizeable losses, negative cash flow, and very high negative return ratios, while the valuation appears rich relative to book value. Short interest and recent news flow indicate heightened attention around positive late-stage clinical trial results, but also ongoing sensitivity to sentiment and data outcomes.
AI summarized at 6:09 PM ET, 2026-02-18
AI summary scores
INTRADAY: 68 SWING: 74 LONG: 39
Volume vs average
Intraday (cumulative)
−22% (Below avg)
Vol/Avg: 0.78×
RSI
52.71 (Neutral)
Neutral (40–60)
MACD momentum
Intraday
+0.01 (Strong)
MACD: 0.02 Signal: 0.01
Short-Term
+0.09 (Strong)
MACD: 0.27 Signal: 0.19
Long-Term
+0.09 (Strong)
MACD: 0.38 Signal: 0.29
Intraday trend score 34.32

Latest news

CMPS 12 articles Positive: 7 Neutral: 0 Negative: 0
Positive Benzinga • Prnewswire
Psychedelic Medicine Advances: Here Are Five Companies Targeting CNS Disorders

The psychedelic medicine sector is advancing with regulatory momentum, as the first psilocybin compound achieved two positive Phase 3 results in treatment-resistant depression. The DEA increased its 2026 psilocybin production quota by 67%. Five companies—Helus Pharma, Compass Pathways, Relmada Therapeutics, Alto Neuroscience, and Axsome Therapeutics—are progressing clinical programs targeting depression, anxiety, cognitive impairment, bladder cancer, and Alzheimer's agitation.

CMPS RLMD ANRO AXSM psychedelic medicine psilocybin treatment-resistant depression Phase 3 trials
Sentiment note

COMP360 achieved two positive Phase 3 trials with highly statistically significant results (p<0.001); 39% of participants achieved clinically meaningful depression reduction; submitted rolling submission request to FDA; durable effects observed through 26 weeks.

Positive The Motley Fool • Howard Smith
Why Did Compass Pathways Stock Rocket Higher Today?

Compass Pathways stock surged 44% after announcing positive Phase 3 clinical trial results for COMP360, its psilocybin-based treatment for treatment-resistant depression. The company plans to submit a New Drug Application (NDA) to the FDA by the end of 2024, with trials involving over 1,000 participants showing statistically significant and clinically meaningful results.

CMPS psilocybin therapy treatment-resistant depression Phase 3 clinical trials FDA approval biotech stock COMP360 New Drug Application
Sentiment note

Stock surged 44% on successful Phase 3 trial results showing statistically significant outcomes for psilocybin treatment. Company plans NDA submission to FDA by end of year, representing a major milestone in the drug approval process for a treatment addressing an underserved patient population with limited options.

Positive The Motley Fool • Eric Volkman
Why Compass Pathways Stock Was a Double-Digit Winner This Week

Compass Pathways, a U.K.-based biotech company focused on psilocybin, has completed dosing in a late-stage clinical trial for its synthesized psilocybin treatment, COMP005. The company is testing the treatment on patients with moderate to severe depression who have not responded to previous treatments. Investors are hopeful for the success of this trial, as the field of psychedelic medicine is seen as having significant potential.

CMPS Compass Pathways psilocybin psychedelic medicine clinical trial depression
Sentiment note

The article highlights Compass Pathways' progress in its late-stage clinical trial for a psilocybin-based treatment, which is seen as a significant milestone in the company's mission to address the unmet need in treatment-resistant depression. The positive sentiment is based on the company's advancement in this trial and the potential of the psychedelic medicine field.

Positive GlobeNewswire Inc. • Delveinsight
Comprehensive Market Analysis of Latest Published Different Types of Depression Reports | DelveInsight

The depression treatment market is experiencing steady growth, driven by rising mental health awareness, increasing prevalence of depression, and advancements in novel therapies. The market is expanding with the introduction of innovative antidepressants, psychedelic-based treatments, and digital therapeutics.

LPCN BRIBY GHRS JNJ depression mental health treatment antidepressants
Sentiment note

COMPASS Pathways is mentioned as a company developing a promising therapy (COMP360) for treatment-resistant depression.

Positive GlobeNewswire Inc. • Globe Newswire
Compass Pathways to participate in three investor conferences in September

Compass Pathways, a biotechnology company focused on mental health, announced its participation in several investor conferences in September 2024, including fireside chats and investor meetings.

CMPS Compass Pathways mental health investor conferences
Sentiment note

The article highlights Compass Pathways' participation in investor conferences, which suggests the company is actively engaging with the investment community and is likely making progress in its mental health-focused initiatives.

Positive Investing.com • Professor Ari Zoldan
4 Psychedelic Stocks to Consider as Clinical Trials Heat up

Several biotechnology firms have psychedelic treatments in development, with promising results from clinical trials. The psychedelic market is expected to grow significantly, and most investors are favorable towards psychedelic stocks.

ATAI CMPS IXHL MNMD psychedelic stocks clinical trials biotechnology mental health
Sentiment note

Compass Pathways is conducting clinical trials for its psilocybin-based treatment for treatment-resistant depression, post-traumatic stress disorder, and anorexia nervosa, with positive results reported.

Positive Investing.com • Emilio Ghigini
Compass Pathways initiated at 'Outperform' by RBC, cites $2.3B revenue potential - Investing.com

RBC Capital initiated coverage on Compass Pathways with an Outperform rating and a $23 price target, citing a high likelihood of positive phase III trial results for its psilocybin-based treatment for treatment-resistant depression and a potential peak revenue of $2.3 billion.

CMPS MS MSPA MSPE Compass Pathways RBC Capital psilocybin treatment-resistant depression
Sentiment note

RBC Capital expects positive phase III trial results and significant revenue potential for Compass Pathways' psilocybin-based treatment for treatment-resistant depression.

Unknown GlobeNewswire Inc. • Compass Pathways
Compass Pathways appoints Lori Englebert as Chief Commercial Officer

LONDON, June 26, 2024 (GLOBE NEWSWIRE) -- Compass Pathways plc (Nasdaq: CMPS) (“Compass”), a biotechnology company dedicated to accelerating access to evidence-based innovation in mental health, today announced the appointment of Lori Englebert as Chief Commercial Officer, effective July 8, 2024. She will be based in the company’s New York City office.

CMPS Directors and Officers Management Changes
Unknown The Motley Fool • newsfeedback@fool.com (Alex Carchidi)
Should You Buy the Dip on Compass Pathways Stock?

Nothing is going wrong, but one of its peers just hit a serious snag.

CMPS investing
Unknown The Motley Fool • newsfeedback@fool.com (Alex Carchidi)
Psychedelics Stocks Are Falling After a Shocking Vote at the FDA. Here's What You Need to Know.

Regulators were not impressed by one company's petition for approval.

CMPS investing
Unknown The Motley Fool • newsfeedback@fool.com (Alex Carchidi)
These 2 Catalysts Could Soon Send Compass Pathways Stock Soaring

Psychedelic medicines are rapidly gaining legitimacy on several fronts.

CMPS investing
Unknown The Motley Fool • newsfeedback@fool.com (Motley Fool Transcribing)
Compass Pathways Plc (CMPS) Q1 2024 Earnings Call Transcript

CMPS earnings call for the period ending March 31, 2024.

CMPS earningscall-transcripts
News and sentiment labels describe article tone and are provided for research purposes only. They are not trading recommendations or forecasts.
Trade Ranks, LLC is not a registered investment adviser or broker-dealer. All rankings and AI reports are for informational and educational purposes only and are not personalized advice. Investing involves risk. Policy Portal