AXSM
Axsome Therapeutics, Inc. · Healthcare · Biotechnology
Last
$236.94
−$0.59 (−0.25%) 4:00 PM ET
After hours $237.04 +$0.10 (+0.04%) 8:43 AM ET
Prev close $237.53
Open $234.27
Day high $240.53
Day low $233.52
Volume 567,431
Avg vol 1,057,534
Mkt cap
$12.22B
P/E ratio
-63.69
FY Revenue
$708.24M
EPS
-3.72
Gross Margin
92.60%
Sector
Healthcare
AI report sections
AXSM
Axsome Therapeutics, Inc.
Axsome Therapeutics exhibits very strong price appreciation over the past year and multiple bullish technical signals, with the share price trading near the top of its 52-week range. At the same time, the company remains loss-making with negative operating and free cash flow margins and elevated valuation multiples. Short interest and recent news tone suggest constructive sentiment, but high volatility and leverage metrics underscore ongoing risk.
AI summarized at 2:27 PM ET, 2026-06-09
AI summary scores
INTRADAY: 68 SWING: 79 LONG: 46
Volume vs average
Intraday (cumulative)
−30% (Below avg)
Vol/Avg: 0.70×
RSI
48.52 (Neutral)
Neutral (40–60)
MACD momentum
Intraday
+0.18 (Strong)
MACD: 0.74 Signal: 0.56
Short-Term
-1.96 (Weak)
MACD: 0.26 Signal: 2.22
Long-Term
-2.04 (Weak)
MACD: 7.51 Signal: 9.56
Intraday trend score 53.11

Latest news

AXSM 12 articles Positive: 10 Neutral: 2 Negative: 0
Positive GlobeNewswire Inc. • Na
Axsome Therapeutics to Report Second Quarter 2026 Financial Results on August 10

Axsome Therapeutics announced it will report Q2 2026 financial results on August 10, 2026, followed by a management conference call at 8:00 a.m. ET. The company is advancing its CNS disorder treatment portfolio with FDA-approved products including SUNOSI, AUVELITY, and SYMBRAVO, while progressing multiple clinical trials including Phase 3 FOCUS-2 and FOCUS-3 trials for solriamfetol in pediatric and adolescent ADHD patients.

AXSM financial results conference call CNS disorders FDA-approved treatments clinical trials ADHD solriamfetol
Sentiment note

The company is expanding its clinical pipeline with initiation of Phase 3 trials (FOCUS-2 and FOCUS-3) for solriamfetol in pediatric and adolescent ADHD populations, demonstrating pipeline advancement and growth potential. The company maintains an established portfolio of FDA-approved CNS treatments and is actively progressing development programs, indicating positive momentum in both commercial and R&D operations.

Positive The Motley Fool • Adria Cimino
These 3 Stocks Trounced the S&P 500 in the First Half of 2026 -- and Wall Street Thinks 1 of Them Could Soar Even More

Three biotech companies—Moderna, Revolution Medicines, and Axsome Therapeutics—significantly outperformed the S&P 500 in the first half of 2026 with double- and triple-digit gains. While Moderna faces expected pullback despite flu vaccine approval prospects, and Revolution Medicines shows modest upside, Wall Street expects Axsome to climb another 13% due to recent drug approvals and strong pipeline progress.

MRNA RVMD RVMDW AXSM biotech stocks S&P 500 performance drug approvals cancer treatment
Sentiment note

Recent approvals for Auvelity (Alzheimer's agitation) and Symbravo (migraine), combined with multiple phase 3 trials and strong commercial drug performance, support Wall Street's 13% upside forecast over the next 12 months.

Positive The Motley Fool • Adria Cimino
Is Axsome Therapeutics Stock a Millionaire Maker? Here's What the Numbers Say.

Axsome Therapeutics has experienced significant growth with its CNS disorder treatments, including recently approved drugs Auvelity for Alzheimer's agitation and Symbravo for migraines. While the stock has climbed 220% over three years and has strong revenue growth, the article cautions that reaching millionaire status from a single stock investment is unrealistic, recommending instead a diversified portfolio approach.

AXSM biotech CNS disorders drug approvals revenue growth clinical trials Alzheimer's disease depression treatment
Sentiment note

Company demonstrates strong commercial momentum with Auvelity revenue up 59% and Sunosi up 34% in recent quarter. Multiple recently approved drugs (Auvelity for Alzheimer's, Symbravo for migraine) and robust late-stage pipeline (AXS-12, solriamfetol, AXS-14) position the company for continued growth. Stock has appreciated 220% over three years and maintains healthy cash position of $305 million.

Positive GlobeNewswire Inc. • Axsome Therapeutics
Axsome Therapeutics Initiates FOCUS-3 Phase 3 Trial of Solriamfetol in Adolescents with Attention Deficit Hyperactivity Disorder (ADHD)

Axsome Therapeutics announced the initiation of the FOCUS-3 Phase 3 trial evaluating solriamfetol for treating ADHD in adolescents aged 12-17. The randomized, double-blind, placebo-controlled trial will enroll approximately 468 patients across multiple centers over 6 weeks, with the primary endpoint measuring changes in ADHD Rating Scale scores.

AXSM ADHD treatment Phase 3 clinical trial solriamfetol adolescents DNRI mechanism biopharmaceutical CNS disorders
Sentiment note

The company is advancing its clinical pipeline with the initiation of a Phase 3 trial for solriamfetol in a new patient population (adolescents with ADHD), demonstrating progress in drug development and expansion of therapeutic indications. This represents a significant milestone in the company's growth strategy and potential market expansion.

Neutral GlobeNewswire Inc. • Hypercharge Networks Corp.
Hypercharge Announces Issuance of Equity Grants

Hypercharge Networks Corp. announced the grant of 2,630,000 stock options at an exercise price of $0.08 and 1,115,464 deferred share units to directors, officers, employees, and consultants. The company also announced it was named co-winner of the Canada Growth Cup and grew its total charging ports by over 45% through the acquisition of Eddie from AXSO, adding over 2,700 ports under management.

AXSM stock options deferred share units equity incentive plan EV charging acquisition Canada Growth Cup
Sentiment note

AXSO is mentioned only as the seller of Eddie charging assets to Hypercharge. No information is provided about AXSO's operations, performance, or strategic implications of the sale.

Positive The Motley Fool • Prosper Junior Bakiny
3 Under-the-Radar Stocks to Buy and Hold for a Decade

The article highlights three biotech companies with strong growth potential over the next decade: Madrigal Pharmaceuticals, which has the first-approved MASH treatment with significant market opportunity; Axsome Therapeutics, which is expanding its depression medicine Auvelity into Alzheimer's disease treatment; and Kailera Therapeutics, a newly public company developing weight-loss medicines in a fast-growing market. All three operate in high-need therapeutic areas with promising pipelines.

MDGL AXSM KLRA NVO biotechnology pharmaceutical stocks MASH treatment depression medicine
Sentiment note

Strong revenue growth (57% YoY), Auvelity showing robust sales with new Alzheimer's disease agitation indication, projected peak sales of $8 billion, and multiple pipeline candidates in development stages.

Positive GlobeNewswire Inc. • Na
Axsome Therapeutics Presents New SYMBRAVO® Data at the Americal Headache Society (AHS) 68th Annual Scientific Meeting

Axsome Therapeutics announced presentations of new clinical data for SYMBRAVO® (meloxicam and rizatriptan) at the American Headache Society's 68th Annual Scientific Meeting in Orlando, FL (June 4-7, 2026). Four poster presentations will showcase efficacy, safety, and comparative effectiveness data from Phase 3 trials MOMENTUM and MOVEMENT, as well as network meta-analysis comparing SYMBRAVO to gepants for acute migraine treatment.

AXSM SYMBRAVO migraine treatment clinical data American Headache Society meloxicam rizatriptan Phase 3 trials
Sentiment note

The company is presenting multiple new clinical data presentations for its FDA-approved migraine treatment SYMBRAVO at a major scientific conference, demonstrating continued clinical validation and market support for the product. The presentations cover efficacy, safety, and comparative advantages, which supports commercial positioning and investor confidence.

Positive GlobeNewswire Inc. • Na
Axsome Therapeutics Partners with the Headache Alliance to Highlight the Impact of Migraine During Migraine and Headache Awareness Month

Axsome Therapeutics announced its support for Migraine and Headache Awareness Month in June 2026, partnering with the Headache Alliance to promote educational initiatives. The company is supporting the first annual 'Headache in the City' campaign on June 15 in New York City and will illuminate its headquarters at One World Trade Center in purple to raise awareness. Axsome also shared resources from leading migraine advocacy organizations to help patients access care and treatment information.

AXSM migraine awareness headache disorders patient education CNS disorders FDA-approved treatments SUNOSI AUVELITY
Sentiment note

The company is actively supporting migraine awareness initiatives and demonstrating commitment to the patient community through educational partnerships, community engagement events, and resource sharing. This reflects positive corporate social responsibility and brand building in the CNS disorders space.

Positive GlobeNewswire Inc. • Not Specified
Axsome Therapeutics to Participate in Upcoming Investor Conferences

Axsome Therapeutics announced its participation in five major investor conferences scheduled for June 2026, including William Blair Growth Stock Conference, Jefferies Global Healthcare Conference, Goldman Sachs Global Healthcare Conference, Oppenheimer CNS and Neuro-Muscular Summit, and UBS Virtual CNS Day. The company will host fireside chats at each event, with webcasts available on its investor relations website.

AXSM investor conferences biopharmaceutical CNS disorders SUNOSI AUVELITY SYMBRAVO FDA approval
Sentiment note

The company is actively engaging with investors through multiple high-profile conferences, demonstrating confidence in its portfolio and market position. The participation in prestigious financial conferences (Goldman Sachs, UBS, Jefferies) and the mention of FDA-approved products (SUNOSI, AUVELITY, SYMBRAVO) with expanding indications suggest positive momentum and investor interest in the company's CNS treatment pipeline.

Positive The Motley Fool • Jeff Siegel
3 Stocks Poised to Disrupt the Healthcare Market by 2030

The healthcare industry is shifting toward data-driven, precision medicine models powered by AI and genomic data. Three companies are positioned to lead this transformation: Tempus AI is building a healthcare data platform with network effects; Recursion Pharmaceuticals is accelerating drug discovery through automation and machine learning; and Axsome Therapeutics is gaining traction with fast-acting CNS treatments, particularly its antidepressant Auvelity.

TEM RXRX AXSM precision medicine healthcare disruption AI in healthcare drug discovery genomic data
Sentiment note

Flagship drug Auvelity shows clinical advantages with rapid onset for depression and recent FDA approval for Alzheimer's agitation; Q1 2026 revenue grew 57% year-over-year to $191.2M with analyst projections of $2B+ in additional annual sales from new indications.

Positive GlobeNewswire Inc. • Na
Axsome Therapeutics to Participate in Upcoming Investor Conferences

Axsome Therapeutics announced its participation in two major investor conferences in May 2026: BofA Securities Health Care Conference on May 12 and RBC Capital Markets Global Healthcare Conference on May 19. The company will host fireside chats at both events, with webcasts available on its investor relations website.

AXSM investor conference biopharmaceutical CNS disorders AUVELITY SUNOSI SYMBRAVO FDA approval
Sentiment note

The company is actively engaging with investors through major conferences and demonstrating strong financial performance with 57% year-over-year revenue growth in Q1 2026. Multiple FDA-approved products and a robust pipeline of candidates indicate business momentum and market confidence.

Neutral Benzinga • Globe Newswire
Hypercharge Grows Total Charging Ports by over 45% Through Acquisition of Eddie from AXSO

Hypercharge Networks Corp. has acquired Eddie, an EV charging network operator, from AXSO, adding over 2,700 charging ports (45% growth) and strengthening its presence in Quebec, Canada's largest EV market. The transaction is non-dilutive and accretive on day one, expected to increase recurring revenue and support Hypercharge's path to profitability.

AXSM EV charging acquisition charging ports Quebec market network expansion recurring revenue electric vehicles
Sentiment note

AXSO divested Eddie to focus on software innovation while maintaining a partnership with Hypercharge. This represents a strategic refocus rather than negative news, allowing AXSO to concentrate on core competencies.

News and sentiment labels describe article tone and are provided for research purposes only. They are not trading recommendations or forecasts.
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