APGE
Apogee Therapeutics, Inc. · Healthcare · Biotechnology
Last
$133.98
−$0.10 (−0.07%) 4:00 PM ET
Prev close $134.08
Open $133.99
Day high $134.20
Day low $133.94
Volume 1,840,283
Avg vol 4,415,563
Mkt cap
$10.14B
P/E ratio
-30.94
EPS
-4.33
Sector
Healthcare
AI report sections
APGE
Apogee Therapeutics, Inc.
No AI report section text found yet for this symbol.
Volume vs average
Intraday (cumulative)
−2% (Below avg)
Vol/Avg: 0.98×
RSI
81.05 (Overbought)
Overbought (>70)
MACD momentum
Intraday
-0.00 (Weak)
MACD: -0.00 Signal: -0.00
Short-Term
-1.18 (Weak)
MACD: 9.97 Signal: 11.15
Long-Term
+0.39 (Strong)
MACD: 15.50 Signal: 15.11
Intraday trend score 30.00

Latest news

APGE 12 articles Positive: 9 Neutral: 0 Negative: 3
Negative GlobeNewswire Inc. • Halper Sadeh Llc
Halper Sadeh LLC is Investigating Whether NEE, CRBG, RMAX, APGE are Obtaining Fair Deals for their Shareholders

Halper Sadeh LLC, an investor rights law firm, is investigating four companies for potential securities law violations and breaches of fiduciary duties related to their proposed mergers and acquisitions. The firm is examining whether shareholders are receiving fair consideration and whether insider benefits may be limiting superior competing offers.

NEE NEEPN NEEPS NEEPT merger investigation shareholder rights fiduciary duty securities law
Sentiment note

Under investigation for potential securities law violations in acquisition by AbbVie; concerns about fair valuation and insider benefits

Positive The Motley Fool • Jonathan Ponciano
What This Apogee Insider Move Might Mean After a 247% Stock Run

Apogee Therapeutics CEO Michael Henderson disposed of 95,046 shares, with 75,046 gifted to charity and 20,000 sold under a pre-established trading plan. Henderson retains 921,000 shares worth ~$123 million. The insider activity is not viewed as a red flag given the CEO's substantial remaining stake. Apogee's lead antibody candidate showed strong Phase 2 data for atopic dermatitis, with Phase 3 trials and head-to-head comparisons against Dupixent expected in late 2026. The company has $1.3 billion in cash funding operations into 2029.

APGE insider trading biotech clinical-stage monoclonal antibodies Phase 3 trials atopic dermatitis COPD
Sentiment note

Strong Phase 2 clinical data for lead candidate with durable responses, substantial cash runway through 2029, upcoming Phase 3 launch and competitive head-to-head trial readouts in late 2026 represent significant near-term catalysts. CEO's retention of $123 million in stock demonstrates confidence. 247% one-year stock performance reflects market optimism despite current net losses.

Positive The Motley Fool • Reuben Gregg Brewer
AbbVie Is Already a Dividend King. Here's Why the $10.9 Billion Apogee Deal Could Make It a Dynasty

AbbVie, a Dividend King, is acquiring Apogee Therapeutics for $10.9 billion to strengthen its drug pipeline and maintain its dividend growth streak. The deal brings late-stage drug candidates like zumilokibart for atopic dermatitis and respiratory drugs, helping AbbVie replace revenue lost from Humira's patent expiration with newer products like Skyrizi and Rinvoq.

ABBV APGE ABT pharmaceutical acquisition dividend growth drug pipeline patent expiration biologics
Sentiment note

Being acquired by a major pharmaceutical company validates Apogee's drug candidates and provides resources for development. The acquisition offers shareholders liquidity and exposure to AbbVie's larger platform.

Negative GlobeNewswire Inc. • Halper Sadeh Llc
Halper Sadeh LLC is Investigating Whether APGE, LPRO, HUN, AVNS are Obtaining Fair Deals for their Shareholders

Investor rights law firm Halper Sadeh LLC is investigating four companies for potential securities law violations and breaches of fiduciary duties related to their proposed acquisitions. The firm is examining whether shareholders are receiving fair consideration and whether insider benefits may be limiting competing offers.

APGE LPRO HUN AVNS securities fraud fiduciary duty shareholder rights mergers and acquisitions
Sentiment note

Under investigation for potential securities law violations and fiduciary duty breaches related to its $135.11 per share sale to AbbVie, suggesting concerns about fair valuation and shareholder treatment.

Positive The Motley Fool • Eric Volkman
AbbVie's $10.9 Billion Apogee Deal Will Extend Its Immunology Dominance: Is It Time to Load Up on This Dividend King?

AbbVie announced a $10.9 billion acquisition of clinical-stage biotech Apogee Therapeutics, paying $135.11 per share in cash. The deal strengthens AbbVie's immunology portfolio with access to promising drug candidates like zumilokibart for eczema and asthma. While the acquisition will create near-term EPS headwinds, analysts expect it to be accretive by 2032 and support AbbVie's dividend yield of over 3%.

ABBV APGE REGN acquisition immunology biotech zumilokibart atopic dermatitis
Sentiment note

Shareholders receive a 47% premium to the previous closing price at $135.11 per share, representing a favorable exit for investors. The company's pipeline, particularly zumilokibart, is described as 'very promising' with strong clinical trial results.

Negative GlobeNewswire Inc. • Brodsky & Smith
BRODSKY & SMITH SHAREHOLDER UPDATE: Notifying Investors of the Following Investigations: Apogee Therapeutics, Inc. (Nasdaq – APGE), Simulations Plus, Inc. (Nasdaq – SLP), Roku, Inc. (Nasdaq – ROKU), TruBridge, Inc. (Nasdaq – TBRG)

Brodsky & Smith law firm has announced investigations into multiple merger transactions, including Apogee Therapeutics (acquired by AbbVie for $135.11/share), Roku (acquired by Fox for $160/share), TruBridge (acquired by Inventurus for $26.25/share), and Organon (acquired by Sun Pharmaceutical for $14/share). The investigations focus on whether the respective boards breached fiduciary duties by failing to conduct fair processes and whether deal consideration provides fair value to shareholders.

APGE ABBV ROKU FOX merger investigation fiduciary duty shareholder litigation deal valuation
Sentiment note

Under investigation for potential board breach of fiduciary duties regarding merger fairness and deal consideration adequacy

Positive The Motley Fool • Jonathan Ponciano
Apogee CEO Sells 20,000 Shares as Stock Surges Nearly 100% in a Year, but Here's What Really Matters for Investors

Apogee Therapeutics CEO Michael Thomas Henderson sold 20,000 shares (~$1.5 million) on March 11, 2026, representing 1.71% of his holdings. The sale was executed under a Rule 10b5-1 plan, suggesting it reflects a pre-planned strategy rather than negative sentiment. Despite the insider sale, the company's stock has surged nearly 100% in the past year. The article emphasizes that investors should focus on Apogee's positive Phase 2 clinical data showing 85% patient response durability, upcoming Phase 3 trials, and a $350 million equity offering that strengthens its balance sheet for late-stage development.

APGE insider sale biotech immunology monoclonal antibodies atopic dermatitis COPD Phase 2 data
Sentiment note

Despite the CEO's insider sale, the article emphasizes positive clinical progress with Phase 2 data showing 85% patient response maintenance and deepening efficacy. The company's $350 million equity offering strengthens its balance sheet, and Phase 3 trials are expected to begin in H2 2026. The stock has surged 98% in one year, and the insider sale under a Rule 10b5-1 plan is characterized as a pre-planned transaction rather than a negative signal. The article concludes investors should focus on execution and clinical results.

Positive GlobeNewswire Inc. • Na
Apogee Therapeutics, Inc. Announces Pricing of $350 Million Underwritten Public Offering

Apogee Therapeutics priced an underwritten public offering of 5 million shares at $70 per share, raising approximately $350 million in gross proceeds. The offering is expected to close on March 26, 2026. The company is a clinical-stage biotech firm developing novel biologics for inflammatory and immunology markets, with its lead program Zumilokibart (APG777) in development for atopic dermatitis, asthma, and eosinophilic esophagitis.

APGE public offering biotechnology capital raise clinical-stage atopic dermatitis biologics inflammatory and immunology
Sentiment note

The company successfully priced a substantial $350 million public offering at $70 per share, demonstrating investor confidence. The offering provides significant capital to advance clinical development of its pipeline, particularly Zumilokibart which showed positive Phase 2 data with durable maintenance of responses in atopic dermatitis treatment.

Positive GlobeNewswire Inc. • Na
Apogee Therapeutics to Host Conference Call to Report Part A 52-Week Data from the Phase 2 APEX Trial of Zumilokibart (APG777) in Patients with Moderate-to-Severe Atopic Dermatitis on March 23, 2026

Apogee Therapeutics announced it will report 52-week Phase 2 APEX trial data for zumilokibart (APG777) in atopic dermatitis patients on March 23, 2026, via conference call at 8:00 a.m. ET. The company is advancing novel biologics targeting inflammatory and immunology markets.

APGE zumilokibart APG777 APEX trial Phase 2 atopic dermatitis clinical trial data biologics
Sentiment note

The company is reporting Phase 2 trial data for its lead candidate zumilokibart, indicating clinical progress. The advancement of trials in multiple indications (AD, asthma, EoE) and the company's focus on best-in-class efficacy demonstrates pipeline momentum and development progress in large market opportunities.

Positive The Motley Fool • Jonathan Ponciano
Apogee Therapeutics Stock Up 100% as Fund Lifts Stake to $28 Million

Great Point Partners increased its stake in Apogee Therapeutics (APGE) by 70,000 shares to 374,000 shares worth $28.23 million, making it the fund's largest holding at 9.15% of assets. APGE stock has doubled over the past year and is advancing monoclonal antibody therapies for inflammatory diseases with Phase 2 atopic dermatitis data expected in H1 2026.

APGE biotech monoclonal antibodies immunology atopic dermatitis COPD clinical trials fund investment
Sentiment note

Stock has doubled over the past year, major fund increased position to largest holding, strong cash position ($913M) with runway to H2 2028, promising interim Phase 1b asthma data showing durable suppression, and Phase 2 atopic dermatitis readouts expected in H1 2026 supporting potential 2029 launch.

Positive GlobeNewswire Inc. • Na
Apogee Therapeutics Announces Positive Interim Results from Phase 1b Trial of Zumilokibart (APG777), its Potentially Best-in-Class Anti-IL-13 Antibody, in Patients with Mild-to-Moderate Asthma and Highlights 2026 Anticipated Milestones and Outlook

Apogee Therapeutics reported positive interim Phase 1b results for zumilokibart (APG777), its anti-IL-13 antibody, in mild-to-moderate asthma patients, demonstrating rapid and durable suppression of FeNO biomarker through 16 weeks with a favorable safety profile. The company also highlighted multiple anticipated 2026 milestones including Phase 2 APEX data readouts in atopic dermatitis and potential Phase 3 initiation by late 2026, with a strong cash position of $913 million supporting operations into H2 2028.

APGE zumilokibart APG777 Phase 1b trial asthma atopic dermatitis FeNO suppression anti-IL-13 antibody
Sentiment note

Company announced positive interim Phase 1b clinical trial results showing favorable safety profile and robust FeNO suppression in asthma patients. Multiple clinical readouts are anticipated in 2026, the company has strong cash position of $913 million with runway into H2 2028, and there is potential for Phase 3 initiation and 2029 launch of lead candidate. The expansion of zumilokibart beyond dermatology into respiratory indications demonstrates pipeline diversification and validates the 'pipeline-in-a-product' strategy.

Positive GlobeNewswire Inc. • Apogee Therapeutics
Apogee Therapeutics Announces Positive Interim Phase 1 Results from Healthy Volunteer Trial of APG333, its Novel Half-Life Extended TSLP Antibody

Apogee Therapeutics reported positive Phase 1 trial results for APG333, a novel half-life extended TSLP antibody, demonstrating a 55-day half-life and potential for quarterly dosing in respiratory treatments.

APGE Phase 1 trial TSLP antibody respiratory treatments biologics immunology
Sentiment note

Successful clinical trial results with promising data on drug half-life, potential dosing frequency, and safety profile

News and sentiment labels describe article tone and are provided for research purposes only. They are not trading recommendations or forecasts.
Trade Ranks, LLC is not a registered investment adviser or broker-dealer. All rankings and AI reports are for informational and educational purposes only and are not personalized advice. Investing involves risk. Policy Portal