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At close
$14.17
+$0.09 (+0.63%) Close
Pre-market$13.95
−$0.22 (−1.55%) 12:22 AM ET
Prev closePrevC$14.08
OpenOpen$14.01
Day highHigh$14.17
Day lowLow$14.01
VolumeVol35
Avg volAvgVol2,252,932
On chart
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Mkt cap
$2.24B
P/E ratio
-35.42
FY Revenue
$276.98M
EPS
-0.40
Gross Margin
74.24%
Sector
Healthcare
AI report sections
MIXED
ADPT
Adaptive Biotechnologies Corporation
Adaptive Biotechnologies combines rapid share-price appreciation and bullish technical signals with ongoing operating losses and negative free cash flow. The stock is trading near the upper end of its 52-week range with improving revenue and earnings trends but also meaningful short interest and competitive pressures in its core MRD market. Overall positioning reflects a constructive intermediate-term trend balanced against execution, cash-flow, and competitive risks.
Adaptive Biotech Insider Sells $554K as Revenue Jumps 55%, but Here's What Investors Should Focus On
Adaptive Biotechnologies' President and COO Julie Rubinstein sold 38,120 shares worth approximately $554,000 through a pre-arranged trading plan. Despite the insider sale, the company reported strong fundamentals with 55% year-over-year revenue growth to $277 million, driven by its MRD segment which now represents over 75% of sales. Net losses narrowed significantly from $159.6 million to $59.5 million, and the MRD segment achieved positive adjusted EBITDA. The article emphasizes that the sale appears compensation-driven rather than a bearish signal, with the real focus being on whether the company can sustain profitability growth.
Strong 55% revenue growth, significant net loss improvement (from $159.6M to $59.5M), MRD segment achieving positive adjusted EBITDA, and 80% stock price appreciation over the past year demonstrate solid business momentum. The insider sale is characterized as compensation-driven rather than a bearish signal, with management guiding for continued growth in 2026.
PositiveThe Motley Fool• Seena Hassouna
Adaptive Biotech's President Trimmed Her Position. But what Remains is worth a look
Adaptive Biotechnologies' President and COO Julie Rubinstein sold 81,342 shares (~$1.21 million) in a pre-scheduled transaction under a 10b5-1 plan, reducing her direct holdings by 11.22%. However, she retains 643,471 shares and over 510,000 vested options. The sale occurred as the stock has gained 51% over the past year. The company's core MRD (Minimal Residual Disease) business achieved 46% revenue growth in 2025 and profitability, with guidance for positive adjusted EBITDA and free cash flow by year-end 2026.
Despite the insider sale, the article emphasizes the company's strong business trajectory with 46% MRD revenue growth in 2025, achievement of profitability, and guidance for positive adjusted EBITDA and free cash flow by end of 2026. The stock has gained 51% over the past year, and the insider's remaining substantial holdings (643,471 shares plus 510,000+ vested options) suggest confidence in the company's future. The sale is characterized as a routine, pre-scheduled liquidity event rather than a loss of confidence.
PositiveThe Motley Fool• Jonathan Ponciano
Adaptive Biotech Insider Sale of 180,000 Shares Tied to Tax Event as Stock Jumps 70% in a Year
Julie Rubinstein, president and COO of Adaptive Biotechnologies, sold 179,703 shares for approximately $2.37 million in March 2026 through a pre-arranged Rule 10b5-1 trading plan tied to tax withholding obligations from RSU vesting. The sale reduced her direct holdings by 26.1%, though she retains substantial stock options. The transaction should not be viewed as a bearish signal, as the company has demonstrated strong momentum with 55% year-over-year revenue growth in 2025, reaching $277 million, and achieving positive adjusted EBITDA and cash flow.
ADPTinsider salestock optionstax withholdingRule 10b5-1 trading planbiotechnologyimmunosequencingMRD business
Sentiment note
Despite insider selling, the company shows strong fundamentals with 55% YoY revenue growth, positive adjusted EBITDA and cash flow, narrowing GAAP losses, and a 72% stock price increase over the past year. The insider sale is attributed to routine tax obligations rather than loss of confidence, and the company's MRD segment and strategic partnerships indicate sustained growth potential.
PositiveBenzinga• Vandana Singh
Pfizer Faces Another Quiet Year As Patent Losses Cloud 2026 Outlook: Analyst
Bank of America expects Pfizer's 2026 financial outlook to remain flat, with challenges from ongoing patent exclusivity losses and limited pipeline catalysts. The company is focusing on areas like obesity treatments, antibody-drug conjugates, and pneumococcal franchise development.
Adaptive Biotechnologies Showcases Leadership in Hematology-Oncology MRD with New clonoSEQ® Data Driving Treatment Interventions at 2025 ASH Annual Meeting
Adaptive Biotechnologies presented 90 abstracts at the ASH Annual Meeting, highlighting its clonoSEQ® test's effectiveness in guiding treatment interventions across multiple blood cancer types, demonstrating precision in measurable residual disease (MRD) monitoring.
Company showcased extensive clinical research across multiple cancer types, demonstrated leadership in MRD testing, and presented data supporting treatment decision-making with its clonoSEQ® technology
NegativeBenzinga• Vandana Singh
Why Is Adaptive Biotechnologies Stock Trading Lower After Natera's Over $400 Million Deal?
Adaptive Biotechnologies' stock dropped after Natera acquired Foresight Diagnostics for $275 million upfront, raising competitive concerns in the blood-cancer minimal residual disease (MRD) market.
ADPTNTRAABTEXASacquisitiononcologyMRDdiagnostics
Sentiment note
Stock dropped 12.63% due to potential competitive threat from Natera's acquisition and reduced M&A speculation after previous Abbott-Exact Sciences deal
PositiveThe Motley Fool• Eric Volkman
Why Adaptive Biotechnologies Stock Popped by Almost 6% on Wednesday
Adaptive Biotechnologies reported strong Q2 2025 results with 36% revenue growth, primarily driven by minimal residual disease (MRD) business. The company beat analyst expectations and raised its MRD revenue guidance for 2025.
Demonstrated strong revenue growth of 36%, beat analyst estimates, narrowed net loss, raised revenue guidance for MRD business, and saw stock price increase by almost 6% following earnings report
U.S. Minimal Residual Disease Testing Market Trends Analysis Report 2025-2033 | Integration with Personalized Medicines, & Rising Incidence and Prevalence of Hematological Malignancies Fueling Growth
The U.S. minimal residual disease testing market is projected to reach $2020 million by 2033, growing at a 9.38% CAGR, driven by rising cancer rates and advancements in precision medicine technologies like NGS and flow cytometry.
Adaptive Biotechnologies Highlights New Data at 2025 ASCO Annual Meeting and EHA 2025 Congress Demonstrating How clonoSEQ® MRD Assessment is Optimizing Patient Care and Drug Development in Lymphoid Cancers
Adaptive Biotechnologies presented new data on the use of its clonoSEQ test for measurable residual disease (MRD) assessment in various blood cancer types at major medical conferences.
The article highlights the company's new data presentations on the clinical utility of its clonoSEQ MRD test, which is being widely adopted in the management of various blood cancers.
Minimal Residual Disease Testing Market Forecast Report, 2025-2030 - Precision Medicine and Early Relapse Detection Drive MRD Testing Demand Worldwide
The Minimal Residual Disease (MRD) Testing Market is expected to grow at a CAGR of 11.18% from 2025 to 2030, driven by advancements in diagnostic technologies and the increasing focus on precision medicine and early relapse detection.
The article highlights Adaptive Biotechnologies Corporation as one of the leading companies driving innovation in the MRD testing market.
PositiveBenzinga• Prnewswire
Cutting-Edge Cancer Therapies Lead the Way into a Transformative Year
The article discusses the promising developments in cancer research, including new therapies and innovative technologies, and highlights recent updates from several biotech companies working on cutting-edge cancer treatments.
ONCYADPTNEOELEVcanceroncologybiotechimmunotherapy
Sentiment note
The article discusses Adaptive Biotechnologies' collaboration with NeoGenomics to expand access to Adaptive's clonoSEQ test for minimal residual disease (MRD) monitoring in blood cancers, which can help oncologists develop more personalized treatment plans.
Adaptive Biotechnologies Announces New Data at the 66th ASH Annual Meeting Highlighting Advances in MRD Testing with clonoSEQ® and Its Impact on Blood Cancer Treatment Decisions
Adaptive Biotechnologies presented new data at the ASH Annual Meeting demonstrating the impact of its clonoSEQ test in assessing minimal residual disease (MRD) and informing treatment decisions for various blood cancers.
The article highlights the company's advancements in MRD testing with clonoSEQ and its impact on improving blood cancer treatment decisions, indicating a positive outlook for the company's technology and its potential to benefit patients.
News and sentiment labels describe article tone and are provided for research purposes only. They are not trading recommendations or forecasts.
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