ADPT
Adaptive Biotechnologies Corporation · Healthcare · Biotechnology
Last
$15.25
+$0.09 (+0.63%) 4:00 PM ET
After hours $15.24 −$0.00 (−0.03%) 8:14 AM ET
Prev close $15.15
Open $14.97
Day high $15.47
Day low $14.75
Volume 1,570,431
Avg vol 1,626,836
Mkt cap
$2.42B
P/E ratio
-46.20
FY Revenue
$295.41M
EPS
-0.33
Gross Margin
75.26%
Sector
Healthcare
AI report sections
ADPT
Adaptive Biotechnologies Corporation
Adaptive Biotechnologies combines rapid share-price appreciation and bullish technical signals with ongoing operating losses and negative free cash flow. The stock is trading near the upper end of its 52-week range with improving revenue and earnings trends but also meaningful short interest and competitive pressures in its core MRD market. Overall positioning reflects a constructive intermediate-term trend balanced against execution, cash-flow, and competitive risks.
AI summarized at 10:57 AM ET, 2026-01-13
AI summary scores
INTRADAY: 68 SWING: 72 LONG: 55
Volume vs average
Intraday (cumulative)
+20% (Above avg)
Vol/Avg: 1.20×
RSI
61.52 (Strong)
Strong (60–70)
MACD momentum
Intraday
-0.01 (Weak)
MACD: -0.01 Signal: 0.00
Short-Term
+0.20 (Strong)
MACD: 0.14 Signal: -0.07
Long-Term
+0.16 (Strong)
MACD: -0.12 Signal: -0.28
Intraday trend score 80.86

Latest news

ADPT 12 articles Positive: 8 Neutral: 3 Negative: 1
Neutral The Motley Fool • Cory Renauer
Harvest Investment Services Dumps 356,000 Adaptive Biotechnologies (ADPT) Shares Worth $5.7 Million

Harvest Investment Services completely exited its position in Adaptive Biotechnologies, selling 356,114 shares worth approximately $5.67 million during Q1 2026. The sale was part of a broader portfolio restructuring where the firm closed 48 positions. Despite the exit, ADPT shares have appreciated 57.78% over the prior year, with strong Q1 growth in cancer diagnostic testing.

ADPT PLTR stock sale position exit biotechnology diagnostics minimal residual disease testing portfolio restructuring
Sentiment note

While the complete exit by Harvest is negative in isolation, the article notes this was part of a broader 48-position portfolio restructuring, suggesting no company-specific concerns. Additionally, ADPT showed strong fundamentals with 53% YoY growth in MRD cancer tests and received its first major milestone payment, indicating positive business momentum despite the institutional investor's exit.

Neutral The Motley Fool • Robert Izquierdo
Adaptive Biotechnologies' Chief Operating Officer Sold Over 19,000 Company Shares. Here's What That Means for Investors.

Adaptive Biotechnologies' COO Julie Rubinstein sold 19,037 shares worth approximately $271,000 on April 27, 2026, as part of a pre-established Rule 10b5-1 trading plan. The sale represented only 4.8% of her holdings, and she maintains significant equity stakes with 377,802 directly-held shares and 45,731 options. The transaction is not considered a red flag, as the company reported strong 55% revenue growth in 2025 while significantly reducing operating losses.

ADPT insider trading stock sale Rule 10b5-1 trading plan biotechnology immunosequencing revenue growth operating losses
Sentiment note

While the insider sale could be viewed negatively, the article emphasizes this is part of a systematic trading plan and not indicative of loss of confidence. The company shows strong fundamentals with 55% revenue growth and significantly improved operating losses. The stock pullback from its 52-week high presents a potential buying opportunity, suggesting the analyst views the company's prospects as stable to positive despite near-term valuation concerns.

Neutral The Motley Fool • Cory Renauer
Should You Sell Adaptive Biotechnologies (ADPT) After Its President and COO Sold 57,000 Shares?

Adaptive Biotechnologies' President and COO Julie Rubinstein sold 57,180 shares (~$826,000) between April 14-16, 2026, through the exercise and immediate sale of stock options. The analyst characterizes this as a liquidity event rather than a loss of confidence, noting Rubinstein retains 408,160 shares and 148,770 options. The company's MRD cancer monitoring revenue grew 46% last year, with expanded Medicare coverage supporting future growth.

ADPT insider sale stock options biotechnology immunosequencing MRD cancer monitoring clonoSEQ executive compensation
Sentiment note

The insider sale is framed as a routine liquidity event from option exercises rather than a bearish signal. The company shows strong fundamentals with 46% revenue growth in MRD services and expanded Medicare coverage. However, the executive's reduction in direct holdings and multiple recent sales warrant cautious monitoring, balancing positive business metrics against insider selling activity.

Positive The Motley Fool • Jonathan Ponciano
Adaptive Biotech Insider Sells $554K as Revenue Jumps 55%, but Here's What Investors Should Focus On

Adaptive Biotechnologies' President and COO Julie Rubinstein sold 38,120 shares worth approximately $554,000 through a pre-arranged trading plan. Despite the insider sale, the company reported strong fundamentals with 55% year-over-year revenue growth to $277 million, driven by its MRD segment which now represents over 75% of sales. Net losses narrowed significantly from $159.6 million to $59.5 million, and the MRD segment achieved positive adjusted EBITDA. The article emphasizes that the sale appears compensation-driven rather than a bearish signal, with the real focus being on whether the company can sustain profitability growth.

ADPT MSFT insider sale revenue growth biotechnology immune diagnostics profitability MRD segment
Sentiment note

Strong 55% revenue growth, significant net loss improvement (from $159.6M to $59.5M), MRD segment achieving positive adjusted EBITDA, and 80% stock price appreciation over the past year demonstrate solid business momentum. The insider sale is characterized as compensation-driven rather than a bearish signal, with management guiding for continued growth in 2026.

Positive The Motley Fool • Seena Hassouna
Adaptive Biotech's President Trimmed Her Position. But what Remains is worth a look

Adaptive Biotechnologies' President and COO Julie Rubinstein sold 81,342 shares (~$1.21 million) in a pre-scheduled transaction under a 10b5-1 plan, reducing her direct holdings by 11.22%. However, she retains 643,471 shares and over 510,000 vested options. The sale occurred as the stock has gained 51% over the past year. The company's core MRD (Minimal Residual Disease) business achieved 46% revenue growth in 2025 and profitability, with guidance for positive adjusted EBITDA and free cash flow by year-end 2026.

ADPT insider sale stock options exercise 10b5-1 trading plan minimal residual disease (MRD) clonoSEQ biotechnology profitability inflection
Sentiment note

Despite the insider sale, the article emphasizes the company's strong business trajectory with 46% MRD revenue growth in 2025, achievement of profitability, and guidance for positive adjusted EBITDA and free cash flow by end of 2026. The stock has gained 51% over the past year, and the insider's remaining substantial holdings (643,471 shares plus 510,000+ vested options) suggest confidence in the company's future. The sale is characterized as a routine, pre-scheduled liquidity event rather than a loss of confidence.

Positive The Motley Fool • Jonathan Ponciano
Adaptive Biotech Insider Sale of 180,000 Shares Tied to Tax Event as Stock Jumps 70% in a Year

Julie Rubinstein, president and COO of Adaptive Biotechnologies, sold 179,703 shares for approximately $2.37 million in March 2026 through a pre-arranged Rule 10b5-1 trading plan tied to tax withholding obligations from RSU vesting. The sale reduced her direct holdings by 26.1%, though she retains substantial stock options. The transaction should not be viewed as a bearish signal, as the company has demonstrated strong momentum with 55% year-over-year revenue growth in 2025, reaching $277 million, and achieving positive adjusted EBITDA and cash flow.

ADPT insider sale stock options tax withholding Rule 10b5-1 trading plan biotechnology immunosequencing MRD business
Sentiment note

Despite insider selling, the company shows strong fundamentals with 55% YoY revenue growth, positive adjusted EBITDA and cash flow, narrowing GAAP losses, and a 72% stock price increase over the past year. The insider sale is attributed to routine tax obligations rather than loss of confidence, and the company's MRD segment and strategic partnerships indicate sustained growth potential.

Positive Benzinga • Vandana Singh
Pfizer Faces Another Quiet Year As Patent Losses Cloud 2026 Outlook: Analyst

Bank of America expects Pfizer's 2026 financial outlook to remain flat, with challenges from ongoing patent exclusivity losses and limited pipeline catalysts. The company is focusing on areas like obesity treatments, antibody-drug conjugates, and pneumococcal franchise development.

PFE ADPT Pfizer patent loss financial guidance pharmaceutical biotech
Sentiment note

Secured two non-exclusive agreements with Pfizer, potentially earning up to $890 million in milestone payments for immune-driven therapeutic research

Positive GlobeNewswire Inc. • Adaptive Biotechnologies Corporation
Adaptive Biotechnologies Showcases Leadership in Hematology-Oncology MRD with New clonoSEQ® Data Driving Treatment Interventions at 2025 ASH Annual Meeting

Adaptive Biotechnologies presented 90 abstracts at the ASH Annual Meeting, highlighting its clonoSEQ® test's effectiveness in guiding treatment interventions across multiple blood cancer types, demonstrating precision in measurable residual disease (MRD) monitoring.

ADPT MRD hematology oncology blood cancer clinical testing
Sentiment note

Company showcased extensive clinical research across multiple cancer types, demonstrated leadership in MRD testing, and presented data supporting treatment decision-making with its clonoSEQ® technology

Negative Benzinga • Vandana Singh
Why Is Adaptive Biotechnologies Stock Trading Lower After Natera's Over $400 Million Deal?

Adaptive Biotechnologies' stock dropped after Natera acquired Foresight Diagnostics for $275 million upfront, raising competitive concerns in the blood-cancer minimal residual disease (MRD) market.

ADPT NTRA ABT EXAS acquisition oncology MRD diagnostics
Sentiment note

Stock dropped 12.63% due to potential competitive threat from Natera's acquisition and reduced M&A speculation after previous Abbott-Exact Sciences deal

Positive The Motley Fool • Eric Volkman
Why Adaptive Biotechnologies Stock Popped by Almost 6% on Wednesday

Adaptive Biotechnologies reported strong Q2 2025 results with 36% revenue growth, primarily driven by minimal residual disease (MRD) business. The company beat analyst expectations and raised its MRD revenue guidance for 2025.

ADPT biotech earnings MRD revenue growth financial performance
Sentiment note

Demonstrated strong revenue growth of 36%, beat analyst estimates, narrowed net loss, raised revenue guidance for MRD business, and saw stock price increase by almost 6% following earnings report

Positive GlobeNewswire Inc. • Researchandmarkets.Com
U.S. Minimal Residual Disease Testing Market Trends Analysis Report 2025-2033 | Integration with Personalized Medicines, & Rising Incidence and Prevalence of Hematological Malignancies Fueling Growth

The U.S. minimal residual disease testing market is projected to reach $2020 million by 2033, growing at a 9.38% CAGR, driven by rising cancer rates and advancements in precision medicine technologies like NGS and flow cytometry.

TWST TMO ILMN ADPT minimal residual disease cancer testing precision medicine NGS
Sentiment note

Highlighted with FDA-cleared MRD tests for multiple cancer types, indicating market leadership

Positive GlobeNewswire Inc. • Adaptive Biotechnologies Corporation
Adaptive Biotechnologies Highlights New Data at 2025 ASCO Annual Meeting and EHA 2025 Congress Demonstrating How clonoSEQ® MRD Assessment is Optimizing Patient Care and Drug Development in Lymphoid Cancers

Adaptive Biotechnologies presented new data on the use of its clonoSEQ test for measurable residual disease (MRD) assessment in various blood cancer types at major medical conferences.

ADPT Adaptive Biotechnologies clonoSEQ MRD multiple myeloma chronic lymphocytic leukemia ASCO EHA
Sentiment note

The article highlights the company's new data presentations on the clinical utility of its clonoSEQ MRD test, which is being widely adopted in the management of various blood cancers.

News and sentiment labels describe article tone and are provided for research purposes only. They are not trading recommendations or forecasts.
Trade Ranks, LLC is not a registered investment adviser or broker-dealer. All rankings and AI reports are for informational and educational purposes only and are not personalized advice. Investing involves risk. Policy Portal